A new gene nested within theduncegenetic unit ofDrosophila melanogaster
| Autor: | Dora Artiaco, Ennio Giordano, Maria Furia, Filomena Anna Digilio, Lino C. Polito |
|---|---|
| Rok vydání: | 1990 |
| Předmět: |
Genetics
Base Sequence Transcription Genetic biology Molecular Sequence Data Restriction Mapping Nucleic acid sequence Intron biology.organism_classification Introns Drosophila melanogaster Transcription (biology) Multigene Family Complementary DNA Drosophilidae Gene expression Animals Amino Acid Sequence Salivary Proteins and Peptides Gene |
| Zdroj: | Nucleic Acids Research. 18:5837-5841 |
| ISSN: | 1362-4962 0305-1048 |
| DOI: | 10.1093/nar/18.19.5837 |
| Popis: | The molecular organization of the dunce gene of Drosophila melanogaster has proved to be particularly complex, with two divergently transcribed genes, Sgs-4 and Pig-1, nested within its 79 kb intron (1). Here we report the identification and the molecular characterization of a third gene nested within the transcription unit of dunce. This newly identified gene is located nearly 6 kb downstream Pig-1, within a more upstream dunce intron. The gene is developmentally regulated and transcribed with the same polarity of dunce; several lines of evidence indicate that it might encode for a salivary gland secreted (Sgs) protein. |
| Databáze: | OpenAIRE |
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