Impact of Trauma System Structure on Injury Outcomes: A Systematic Review and Meta-Analysis
| Autor: | Amy C. Gunning, Gerard O'Reilly, Christine Gaarder, Teegwendé V. Porgo, Fikri M. Abu-Zidan, Henry T. Stelfox, Howard R. Champion, Cameron S Palmer, John B. Kortbeek, Raul Coimbra, Monty Khajanchi, Vanessa K. Noonan, Malcolm R. Gordon, Luke P. H. Leenen, Lynne Moore, Pier-Alexandre Tardif, Brice Lionel Batomen Kuimi, Alexis F. Turgeon, Peter Cameron, Natalie L. Yanchar, Belinda J. Gabbe, Ari Leppäniemi |
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| Rok vydání: | 2017 |
| Předmět: |
medicine.medical_specialty
Emergency Medical Services MEDLINE Odds 03 medical and health sciences 0302 clinical medicine Physical medicine and rehabilitation Trauma Centers medicine Emergency medical services Humans 030212 general & internal medicine Hospital Mortality Surgeons business.industry Major trauma 030208 emergency & critical care medicine Retrospective cohort study Odds ratio Length of Stay medicine.disease 3. Good health Advanced trauma life support Meta-analysis Emergency medicine Wounds and Injuries Surgery business |
| Zdroj: | World journal of surgery. 42(5) |
| ISSN: | 1432-2323 |
| Popis: | The effectiveness of trauma systems in decreasing injury mortality and morbidity has been well demonstrated. However, little is known about which components contribute to their effectiveness. We aimed to systematically review the evidence of the impact of trauma system components on clinically important injury outcomes. We searched MEDLINE, EMBASE, Cochrane CENTRAL, and BIOSIS/Web of Knowledge, gray literature and trauma association Web sites to identify studies evaluating the association between at least one trauma system component and injury outcome. We calculated pooled effect estimates using inverse-variance random-effects models. We evaluated quality of evidence using GRADE criteria. We screened 15,974 records, retaining 41 studies for qualitative synthesis and 19 for meta-analysis. Two recommended trauma system components were associated with reduced odds of mortality: inclusive design (odds ratio [OR] = 0.72 [0.65–0.80]) and helicopter transport (OR = 0.70 [0.55–0.88]). Pre-Hospital Advanced Trauma Life Support was associated with a significant reduction in hospital days (mean difference [MD] = 5.7 [4.4–7.0]) but a nonsignificant reduction in mortality (OR = 0.78 [0.44–1.39]). Population density of surgeons was associated with a nonsignificant decrease in mortality (MD = 0.58 [−0.22 to 1.39]). Trauma system maturity was associated with a significant reduction in mortality (OR = 0.76 [0.68–0.85]). Quality of evidence was low or very low for mortality and healthcare utilization. This review offers low-quality evidence for the effectiveness of an inclusive design and trauma system maturity and very-low-quality evidence for helicopter transport in reducing injury mortality. Further research should evaluate other recommended components of trauma systems and non-fatal outcomes and explore the impact of system component interactions. |
| Databáze: | OpenAIRE |
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