Hypopigmented lesions in pityriasis lichenoides chronica patients: Are they only post-inflammatory hypopigmentation?
| Autor: | Dina Ahmed El Sharkawy, Dalia M. Abdel Halim, Maha Fathy Elmasry, Mona R. E. Abdel-Halim, Amira Elbendary, AbdAllah Gad, Randa Youssef |
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| Rok vydání: | 2021 |
| Předmět: |
Adult
Male medicine.medical_specialty Adolescent Dermatology Stain Pityriasis Lichenoides Post-inflammatory hypopigmentation Pityriasis lichenoides chronica medicine Humans Child Hypopigmentation medicine.diagnostic_test business.industry medicine.disease Cross-Sectional Studies Child Preschool Hypopigmented macules Skin biopsy Female Active treatment medicine.symptom business |
| Zdroj: | The Australasian journal of dermatologyREFERENCES. 63(1) |
| ISSN: | 1440-0960 |
| Popis: | BACKGROUND/OBJECTIVES Pityriasis lichenoides chronica (PLC) lesions are reported to subside with post-inflammatory hypopigmentation (PIH); hence, the most widely perceived nature of hypopigmented macules in PLC is PIH. However, to the best of our knowledge, no studies describing histopathological findings in these lesions are reported in literature. The aim of this study is to evaluate the hypopigmented lesions encountered in PLC patients and to shed light on their histopathological features. METHODS A cross-sectional observational study included twenty-one patients with PLC recruited in a period of twelve months. Clinical characteristics of each patient were collected. A skin biopsy from hypopigmented lesions whenever present was taken and assessed with routine haematoxylin and eosin stain. RESULTS Seventeen patients (81%) were less than 13 years old. Most patients (85.7%) demonstrated diffuse distribution of lesions. Hypopigmented lesions were present on the face in 12 (57.14%) patients. Histopathologically, hypopigmented lesions showed features of post-inflammatory hypopigmentation in 19% of patients, residual PLC in 52.4% and active PLC 28.6% of patients. CONCLUSION Hypopigmented lesions in PLC were noted mainly in younger ages, histopathologically they may show features of active or residual disease, beyond post-inflammatory hypopigmentation. Consequently active treatment for patients presenting predominantly with hypopigmented lesions could be required to control the disease. |
| Databáze: | OpenAIRE |
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