A 40–100 MHz B-scan ultrasound backscatter microscope for skin imaging
| Autor: | John L. Semple, F. Stuart Foster, Brian Starkoski, Daniel H. Turnbull, Kasia Harasiewicz, Lynn From, Daniel N. Sauder, Aditya K. Gupta |
|---|---|
| Rok vydání: | 1995 |
| Předmět: |
Seborrheic keratosis
Pathology medicine.medical_specialty Skin Neoplasms Microscope Hydrocarbons Fluorinated Acoustics and Ultrasonics Backscatter Transducers Biophysics Skin Diseases Skin Aging law.invention law Psoriasis medicine Humans Radiology Nuclear Medicine and imaging Melanoma Neoplasm Staging Skin Ultrasonography Microscopy integumentary system Radiological and Ultrasound Technology business.industry Ultrasound Resolution (electron density) Signal Processing Computer-Assisted Equipment Design Image Enhancement medicine.disease Dermatitis Seborrheic Polyvinyls business Analog-Digital Conversion Biomedical engineering |
| Zdroj: | Ultrasound in Medicine & Biology. 21:79-88 |
| ISSN: | 0301-5629 |
| Popis: | There is a growing interest in high resolution, subsurface imaging of cutaneous tissues using higher frequency ultrasound, and several commercial systems have been developed recently which operate at 20 MHz. Some of the possible applications of higher frequency skin imaging include tumour staging, boundary definition, and studies of the response of tumours to therapy, investigations of inflammatory skin conditions such as psoriasis and eczema, and basic studies of skin aging, sun damage and the effects of irritants. Investigation of these areas is quite new, and the role of ultrasound skin imaging is continuing to evolve. Lateral resolution in the 20 MHz imaging systems ranges from 200 to 300 microns, which limits imaging applications to cutaneous structures which are relatively large in size. In this paper, a real-time ultrasound backscatter microscope (UBM) for skin imaging is described which operates in the 40-100 MHz range, providing axial resolution between 17 and 30 microns and lateral resolution between 33 and 94 microns. This improvement in resolution over current skin ultrasound systems should prove useful in determining the margins of small skin lesions, and in obtaining more precise, in vivo skin thickness measurements to characterize nonmalignant skin disease. Example images of normal skin, seborrhoeic keratosis and malignant melanoma illustrate the imaging potential of this system. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|