Fibroadipose vascular anomaly treated with sirolimus: Successful outcome in two patients
| Autor: | William McAuliffe, Anne R Halbert, Lewis Blennerhassett, Jonathan Erickson |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
medicine.medical_specialty
Adolescent Vascular Malformations Pain Dermatology 030204 cardiovascular system & hematology Vascular anomaly 03 medical and health sciences 0302 clinical medicine Quality of life medicine Humans Pain Management Severe pain Pediatric dermatology Child Muscle Skeletal Sirolimus Foot business.industry Vascular malformation medicine.disease Magnetic Resonance Imaging Localized swelling Surgery Forearm Treatment Outcome 030220 oncology & carcinogenesis Pediatrics Perinatology and Child Health Quality of Life Female Contracture medicine.symptom business Immunosuppressive Agents medicine.drug |
| Zdroj: | Pediatric Dermatology. 34:e317-e320 |
| ISSN: | 0736-8046 |
| DOI: | 10.1111/pde.13260 |
| Popis: | Fibroadipose vascular anomaly (FAVA) is a rare, complex mesenchymal malformation combining fibrofatty replacement of the affected muscles and slow-flow vascular malformation. The condition is characterized by localized swelling, severe pain, phlebectasia, and contracture of the affected limb. Treatment paradigms are not well established for this rare, recently recognized condition. We report two cases of FAVA in which treatment with sirolimus produced rapid, dramatic improvement in pain and quality of life. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Plný text