Electrochemical Amplification in Side-by-Side Attoliter Nanogap Transducers
| Autor: | Klaus Mathwig, Ernst J. R. Sudhölter, Hamid Reza Zafarani, Liza Rassaei |
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| Přispěvatelé: | Pharmaceutical Analysis, Medicinal Chemistry and Bioanalysis (MCB) |
| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: |
Letter
Materials science electrochemical sensor Bioengineering Nanotechnology nanogap sensor 02 engineering and technology 010402 general chemistry nanofluidics 01 natural sciences Signal generator-collector electrodes Instrumentation Voltammetry Lithography Fluid Flow and Transfer Processes Process Chemistry and Technology redox cycling Amplification factor 021001 nanoscience & nanotechnology 0104 chemical sciences Electrochemical gas sensor Nanolithography Transducer Electrode nanofabrication 0210 nano-technology |
| Zdroj: | ACS Sensors, 2(6), 724-728. AMER CHEMICAL SOC INC ACS Sensors ACS Sensors, 2(6) |
| ISSN: | 2379-3694 |
| Popis: | We report a strategy for the fabrication of a new type of electrochemical nanogap transducer. These nanogap devices are based on signal amplification by redox cycling. Using two steps of electron-beam lithography, vertical gold electrodes are fabricated side by side at a 70 nm distance encompassing a 20 attoliter open nanogap volume. We demonstrate a current amplification factor of 2.5 as well as the possibility to detect the signal of only 60 analyte molecules occupying the detection volume. Experimental voltammetry results are compared to calculations from finite element analysis. |
| Databáze: | OpenAIRE |
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