Diet-induced thermogenesis in patients with gastrointestinal cancer cachexia
| Autor: | NS Williams, Pmt Weston, Rfgj King, AW Goode |
|---|---|
| Rok vydání: | 1989 |
| Předmět: |
Male
medicine.medical_specialty Cachexia Diet induced thermogenesis Adenocarcinoma Weight loss Internal medicine Weight Loss medicine Humans Resting energy expenditure Gastrointestinal cancer Aged Gastrointestinal Neoplasms Chemistry Calorimetry Indirect General Medicine Middle Aged medicine.disease Diet Endocrinology Basal metabolic rate Lean body mass Female Basal Metabolism medicine.symptom Energy Intake Thermogenesis Body Temperature Regulation |
| Zdroj: | Clinical science (London, England : 1979). 77(2) |
| ISSN: | 0143-5221 |
| Popis: | 1. Indirect calorimetry has been used to measure resting energy expenditure (REE) and the thermogenic response to a test meal (diet-induced thermogenesis) in groups of weight-stable and weight-losing patients with gastrointestinal adenocarcinoma. Average daily intakes of energy and protein were computed from dietary assessment for the week before hospitalization. Results were compared with a control group of patients with benign gastrointestinal disease. 2. Weight-losing cancer patients had a significantly reduced mean total energy and protein intake. 3. There was no significant difference in REE between the groups when results were normalized in terms of metabolic body size (kJ/kg 0.75) and lean body mass (kJ/kg). 4. Diet-induced thermogenesis was reduced in weight-losing cancer patients. 5. It is suggested that the reduction of diet-induced thermogenesis in weight-losing cancer patients is another element of starvation adaptation, subsequent to their weight loss, and that altered thermogenesis does not contribute to the weight loss seen in cancer cachexia. |
| Databáze: | OpenAIRE |
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