Quantitative power Doppler signal assessment in the subchondral bone region of the metacarpophalangeal joint is an effective predictor of radiographic progression in the hand of rheumatoid arthritis: a pilot study
| Autor: | Kenneth Sutherland, Kazuhide Tanimura, Akihiro Narita, Motoshi Fujimori, Mutsumi Nishida, Yuki Tanaka, Tatsuya Atsumi, Tamotsu Kamishima, Masaru Kato, Lu Yutong, Mihoko Henmi |
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| Rok vydání: | 2019 |
| Předmět: |
Adult
Male medicine.medical_specialty Time Factors Radiography Immunology Arthritis Pilot Projects Severity of Illness Index Arthritis Rheumatoid Metacarpophalangeal Joint 03 medical and health sciences 0302 clinical medicine Vascularity Rheumatology Predictive Value of Tests Synovitis Internal medicine medicine Humans Immunology and Allergy 030212 general & internal medicine Bone Ultrasonography Aged Retrospective Studies Observer Variation 030203 arthritis & rheumatology Receiver operating characteristic business.industry Reproducibility of Results Ultrasonography Doppler Metacarpophalangeal joint Middle Aged Hand medicine.disease medicine.anatomical_structure Antirheumatic Agents Rheumatoid arthritis Disease Progression Female medicine.symptom Nuclear medicine business |
| Zdroj: | Rheumatology International. 39:1413-1421 |
| ISSN: | 1437-160X 0172-8172 |
| Popis: | Ultrasonography is useful for assessment of synovitis in the hand of rheumatoid arthritis (RA) patients. The aim of this study was to investigate the predictive value of the quantitative power Doppler (PD) signal assessment in the subchondral bone region of the metacarpophalangeal (MCP) joint in patients with RA showing radiographic progression of the hand by comparing with those of previously reported scoring systems. Twenty-two patients (20 women) with RA who underwent power Doppler ultrasonography (PDUS) of the bilateral one to five MCP joints at baseline were included in the study. Radiography of both hands was performed at baseline and at 1 year. PDUS of the synovial space was evaluated according to semi-quantitative scoring (0–3) and quantitative measurement (0–100%). The PD signal in the subchondral bone region was qualitatively (0, 1) and quantitatively (mm2) assessed. The performance of PDUS assessment was compared using the area under the curve (AUC) of the receiver operating characteristic (ROC) curve and the risk ratio (RR). As a predictor for radiographic progression, the quantitative PD signal assessment in the subchondral bone region (AUC = 0.842, p |
| Databáze: | OpenAIRE |
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