High Resolution M-mode Evaluation of Jugular Vein Valves in Patients with Neurological and Neurosensory Disorders

Autor: Francesco Sisini, Sergio Gianesini, Stefano Pelucchi, Andrea Ciorba, Erica Menegatti, Paolo Zamboni, Mirko Tessari, Maria Elena Vannini, Fabrizio Salvi, Manuela Mazzoli, Anna Maria Malagoni
Rok vydání: 2018
Předmět:
Zdroj: Current Neurovascular Research. 14:316-322
ISSN: 1567-2026
Popis: BACKGROUND High prevalence of valve absence was found in the internal jugular vein (IJV) of healthy volunteers by means of M-mode high-resolution Echo Colour Doppler (ECD). However, the prevalence of valve in neurovascular disorders linked to Chronic Cerebrospinal Venous Insufficiency (CCSVI) is still unknown. METHODS A cohort of 83 Healthy Controls (HC), 71 Multiple Sclerosis (MS), 99 Inner Ear Disorders (IED) underwent ECD investigation of the IJV valve, including M-mode evaluation and related hemodynamics. The primary outcome measure was characterization of valve presence, morphology and motility, whereas the secondary outcome was the rate of flow alteration. RESULTS Bilateral valve presence was found in 38% of HC, 58% of MS and 25% of IED, whereas, bilateral valve absence was recorded in 16% of HC, 10% of MS and 31% of IED (p
Databáze: OpenAIRE