| Autor: |
Yan Yan, Carl Schmidt, Konstantinos I. Votanopoulos, Clifford S. Cho, William G. Hawkins, Malcolm H. Squires, David A. Kooby, Emily R. Winslow, George A. Poultsides, Lindsey E. Moses, Mark Bloomston, Ryan C. Fields, Neil Saunders, Linda X. Jin, Shishir K. Maithel, David C. Linehan, Edward A. Levine, Dominic E. Sanford, Sharon M. Weber, Alexandra W. Acher, Graham A. Colditz, Kenneth Cardona, David J. Worhunsky, Gaya Spolverato, Timothy M. Pawlik |
| Jazyk: |
angličtina |
| Rok vydání: |
2016 |
| Předmět: |
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| Popis: |
Postoperative complications (POCs) can negatively impact survival after oncologic resection. POCs may also decrease the rate of adjuvant therapy completion. We evaluated the impact of complications on gastric cancer survival and analyzed the combined effect of complications and adjuvant therapy on survival. We analyzed 824 patients from 7 institutions of the U.S. Gastric Cancer Collaborative who underwent curative resection for gastric adenocarcinoma between 2000 and 2012. POC were graded using the modified Clavien–Dindo system. Survival probabilities were estimated using the method of Kaplan and Meier and analyzed using multivariate Cox regression. Median follow-up was 35 months. The overall complication rate was 41 %. The 5-year overall survival (OS) and recurrence-free survival (RFS) of patients who experienced complications were 27 and 23 %, respectively, compared with 43 and 40 % in patients who did not have complications (p |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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