Chemical composition and biological properties of Rhododendron anthopogon essential oil

Autor: Maria Carrara, Mariagnese Barbera, Khilendra Gurung, Giuditta Scialino, Stefano Dall'Acqua, Gabbriella Innocenti, Silvio Sosa, Elena Banfi
Přispěvatelé: Innocenti, G., Dall'Acqua, S., Scialino, Giuditta, Banfi, Elena, Sosa, Silvio, Gurung, K., Barbera, M., Carrara, M.
Jazyk: angličtina
Rok vydání: 2010
Předmět:
Antifungal Agents
Antitubercular Agents
Pharmaceutical Science
topical anti-inflammatory activity
Bacillus subtilis
medicine.disease_cause
Analytical Chemistry
law.invention
chemistry.chemical_compound
Mice
law
Drug Discovery
Food science
anti-inflammatory activity
Candida
biology
Strain (chemistry)
Chemistry
Anti-Inflammatory Agents
Non-Steroidal
Rhododendron anthopogon
GC-MS
essential oil
antimicrobial activity
antiproliferative activity
Anti-Bacterial Agents
Chemistry (miscellaneous)
Staphylococcus aureus
Molecular Medicine
Rhododendron
Mice
Inbred Strains
Sesquiterpene
Article
Gas Chromatography-Mass Spectrometry
Mycobacterium tuberculosis
lcsh:QD241-441
lcsh:Organic chemistry
Cell Line
Tumor
Botany
medicine
Oils
Volatile
Animals
Humans
Physical and Theoretical Chemistry
Essential oil
Cell Proliferation
Limonene
Bacteria
Organic Chemistry
biology.organism_classification
Gas chromatography–mass spectrometry
Zdroj: Molecules
Molecules, Vol 15, Iss 4, Pp 2326-2338 (2010)
Molecules; Volume 15; Issue 4; Pages: 2326-2338
Popis: The essential oil of Rhododendron anthopogon was investigated by GC-MS, and seventeen compounds (representing approximately 98% of the oil) were identified. The major components of the aerial parts of the oil were the monoterpenes alpha-pinene, beta-pinene, limonene and the sesquiterpene delta-cadinene. Biological studies revealed a weak topical anti-inflammatory activity; a significant killing effect against some Gram-positive reference strains: Staphylococcus aureus, Enterococcusfecalis, Bacillus subtilis was measured; Mycobacterium tuberculosis reference strain and a clinical isolate of Candida, C. pseudotropicalis were killed by as low as 0.04% (v/v) essential oil. Moreover, the oil was able to reduce cancer cell growth independently of the cell line and the treatment protocols used.
Databáze: OpenAIRE
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