Pesticide exposure and cognitive decline in a rural South Korean population

Autor: Sungjin Park, Changsoo Kim, Jae Yeop Kim, Sang Baek Koh, Sung Soo Oh, Tae Hei Kim, Seong Ho Min, Sung Kyung Kim
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Social Sciences
010501 environmental sciences
Alzheimer's Disease
01 natural sciences
Geographical Locations
0302 clinical medicine
Sociology
Medicine and Health Sciences
Medicine
Cognitive decline
Cognitive Impairment
Alcohol Consumption
Multidisciplinary
Cognitive Neurology
Agriculture
Neurodegenerative Diseases
Professions
Neurology
Agricultural Workers
Cognitive Assessment System
Agrochemicals
Research Article
Cohort study
Group based
Asia
Cognitive Neuroscience
Science
Education
03 medical and health sciences
Mental Health and Psychiatry
Pesticides
Educational Attainment
Nutrition
0105 earth and related environmental sciences
Korea
business.industry
Korean population
Biology and Life Sciences
Odds ratio
Pesticide
Confidence interval
Diet
People and Places
Cognitive Science
Dementia
Population Groupings
Pest Control
business
030217 neurology & neurosurgery
Neuroscience
Demography
Zdroj: PLoS ONE, Vol 14, Iss 3, p e0213738 (2019)
PLoS ONE
ISSN: 1932-6203
Popis: We aimed to investigate the relationship between pesticide exposure and cognitive decline in a rural South Korean population. From July 2015 to December 2017, 200 randomly selected Korean Farmers Cohort study participants were recruited and of these, 169 participants were analyzed. Pesticide exposure was investigated using a standardized questionnaire, and the Korean-Montreal Cognitive Assessment (K-MoCA) was conducted. Cognitive decline was more frequent among those directly exposed to pesticides (P = 0.057). Pesticide exposure and cognitive decline were positively correlated in the group with direct exposure versus no exposure (crude odds ratio [OR], 2.66; 95% confidence interval [CI], 1.17–6.04); this relationship was insignificant after adjustment (adjusted OR, 1.50; 95% CI, 0.57–3.92). There was a significant difference in the K-MoCA scores for each group based on pesticide exposure (P = 0.003). When we stratified by age, differences in the K-MoCA scores depending on the degree of pesticide exposure in the those aged 60 to 69 years were identified. Overall, there was a tendency towards an association between pesticide exposure and cognitive decline in rural Korean adult farmers. In our study, chronic pesticide exposure tended to have a greater impact in certain age group (60–69 years) than in those under 60 and over 70.
Databáze: OpenAIRE
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