Effects of dietary supplementation with oridonin on the growth performance, relative organ weight, lymphocyte proliferation, and cytokine concentration in broiler chickens
Autor: | Qiu Jue Wu, Xiao Chuan Zheng, Tie Ying Zhang, Tian Wang |
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Rok vydání: | 2017 |
Předmět: |
0301 basic medicine
Male medicine.medical_specialty animal structures medicine.medical_treatment Lymphocyte Spleen Lymphocyte proliferation Biology 03 medical and health sciences Immune system Bursa of Fabricius Internal medicine medicine Animals Lymphocytes Cytokine Cell Proliferation lcsh:Veterinary medicine General Veterinary Dose-Response Relationship Drug Broiler 0402 animal and dairy science 04 agricultural and veterinary sciences General Medicine Organ Size Phagocytisis of neutrophils 040201 dairy & animal science Diet 030104 developmental biology medicine.anatomical_structure Endocrinology Dietary Supplements lcsh:SF600-1100 Cytokines Tumor necrosis factor alpha Diterpenes Kaurane Chickens Oridonin Research Article |
Zdroj: | BMC Veterinary Research BMC Veterinary Research, Vol 14, Iss 1, Pp 1-6 (2018) |
ISSN: | 1746-6148 |
Popis: | Background The present study was conducted to investigate the effects of oridonin (ORI) on growth performance, relative organ weight, lymphocyte proliferation, phagocytic function of neutrophils, and cytokine concentration in broiler chickens. A total of 240 one-day-old Arbor Acres male broilers were randomly assigned to four treatments with six replicate pens of 10 broiler chickens per pen. Broiler chickens were fed diets based on four levels of dietary ORI (0, 50, 80 and 100 mg/kg) for a 42-d feeding trial. The experimental diets were fed in three phases: 1 to 14 d, 15 to 28 d and 29 to 42 d. Results The results indicated that ORI has no influence on the growth performance (P > 0.05). However, ORI increased the relative weights of spleen and bursa, the number of proliferation peripheral blood T and B lymphocytes, the phagocytic rate of neutrophils, as well as the Interleukin-2 (IL-2), Interleukin-4 (IL-4) and tumor necrosis factor-a (TNF-a) serum concentrations in serum in broilers at days 14, 28 and 42 (P |
Databáze: | OpenAIRE |
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