A Case of Topical Ofloxacin-Induced Otomycosis and Literature Review
| Autor: | Yuya Shimizu, Rima Zakzuk Alshahni, Koichi Makimura, Takashi Tamura, Ryuichi Fujisaki, Chiaki Yamanishi, Mohamed Mahdi Alshahni |
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| Rok vydání: | 2021 |
| Předmět: |
Ofloxacin
medicine.medical_specialty medicine.drug_class Veterinary (miscellaneous) Secondary infection Antibiotics Otomycosis Candida parapsilosis Applied Microbiology and Biotechnology Microbiology Medical microbiology medicine Humans Malassezia integumentary system biology business.industry Fungi Otitis Externa Isolation (microbiology) biology.organism_classification medicine.disease Dermatology business Agronomy and Crop Science medicine.drug |
| Zdroj: | Mycopathologia. 186:871-876 |
| ISSN: | 1573-0832 0301-486X |
| DOI: | 10.1007/s11046-021-00581-x |
| Popis: | The prevalence of fungal otitis externa, or otomycosis, has been increasing in recent decades. Fungi may act as primary pathogens in this condition, or they may occur as secondary infections after prolonged ototopical treatment with antibiotics, which alters the flora of the external auditory canal (EAC) and enables overgrowth of its fungal inhabitants. We report here a case of otomycosis by Candida parapsilosis, Malassezia obtusa, and Malassezia furfur as a secondary infection following prolonged otic ofloxacin treatment. To the best of our knowledge, although isolation of C. parapsilosis and M. furfur from the EAC is not uncommon, the recovery of M. obtusa has not yet been reported. We also conducted a literature review of the searchable data on PubMed concerning the isolation of Malassezia species from the human EAC. |
| Databáze: | OpenAIRE |
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