The Efficacy of Assisted Reproduction in Women with a Wide Spectrum of Chronic Diseases – A Review
| Autor: | Michael Larsen, Sonia Friedman, Jens Fedder, Laura Catalini, Bente Mertz Nørgård, Line Riis Jølving |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
rheumatoid arthritis
Pediatrics medicine.medical_specialty Epidemiology medicine.medical_treatment Disease Review Inflammatory bowel diseases 030204 cardiovascular system & hematology multiple sclerosis inflammatory bowel diseases Multiple sclerosis 03 medical and health sciences Epilepsy Diabetes mellitus 0302 clinical medicine assisted reproductive technology medicine thyroid disease 030212 general & internal medicine Rheumatoid arthritis Assisted reproductive technology business.industry Thyroid disease medicine.disease Ulcerative colitis diabetes mellitus epilepsy business Live birth |
| Zdroj: | Clinical Epidemiology Nørgård, B M, Catalini, L, Jølving, L R, Larsen, M D, Friedman, S & Fedder, J 2021, ' The efficacy of assisted reproduction in women with a wide spectrum of chronic diseases – a review ', Clinical Epidemiology, vol. 13, pp. 477-500 . https://doi.org/10.2147/CLEP.S310795 |
| ISSN: | 1179-1349 |
| DOI: | 10.2147/CLEP.S310795 |
| Popis: | Assisted reproductive technology (ART) treatments in women with underlying chronic diseases have become increasingly frequent. The objective of this review is to provide an overview of the literature examining the chance of having a live born child after ART in women with chronic diseases, compared to other women receiving ART. We focused on some of the most prevalent chronic diseases in women during their reproductive years, ie ulcerative colitis, Crohn’s disease, rheumatoid arthritis, multiple sclerosis, epilepsy, hyperthyroidism, hypothyroidism, and diabetes mellitus. Secondly, we studied the chance of successful implantation. The literature search was performed in the database Pubmed.gov. including all studies published before October 2020. Title and abstracts of 58 papers were reviewed, 37 papers were excluded and other 8 studies were excluded after full-text evaluation. Only 13 papers were eligible for review. Results indicate that women with ulcerative colitis, Crohn’s disease, rheumatoid arthritis, hyperthyroidism, and diabetes mellitus type 2 might have problems with low implantation rate or early embryo development during ART. On the contrary, the few studies on women with hypothyroidism, diabetes mellitus type 1, and epilepsy suggest an equivalent chance of a live birth compared to other women undergoing ART. A possible explanation behind these differences could reside in the disease-specific dysregulation of the innate or adaptive immune system. To our knowledge, this is the first review on ART in women with chronic diseases, and it has disclosed that the evidence in this area is indeed sparse. We encourage others to examine live birth after ART in women with chronic diseases. |
| Databáze: | OpenAIRE |
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