Finite element prediction of endosteal and periosteal bone remodelling in the turkey ulna: Effect of remodelling signal and dead-zone definition
| Autor: | William R. Taylor, Sally E Clift, M D Warner |
|---|---|
| Rok vydání: | 2003 |
| Předmět: |
Turkeys
Materials science Finite Element Analysis Ulna Dead zone Mechanotransduction Cellular Models Biological Sensitivity and Specificity Signal Feedback Bone remodeling Weight-Bearing Physical Stimulation Tensile Strength medicine Animals Principal stress Computer Simulation Bone geometry business.industry Mechanical Engineering Reproducibility of Results General Medicine Structural engineering Finite element method medicine.anatomical_structure Nonlinear Dynamics Bone Remodeling Stress Mechanical business Algorithms Bone mass |
| Zdroj: | Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine. 217:349-356 |
| ISSN: | 2041-3033 0954-4119 |
| DOI: | 10.1243/095441103770802513 |
| Popis: | Bone remodelling is the adaptation of bone mass in response to localized changes in loading conditions. The nature of the mechanical signal governing remodelling, however, remains the subject of continued investigation. The aims of this study were to use an iterative finite element (FE) bone remodelling technique to explore the effect of different remodelling signals in the prediction of bone remodelling behaviour. A finite element model of the turkey ulna, following that of Brown et al., was analysed using the ABAQUS package. The model was validated against the static predictions of the Brown et al. study. A bone remodelling technique, based on swelling algorithms given by Taylor and Clift, was then applied to predict the dramatic change in loading conditions imposed. The resulting changes in FE mid-shaft bone geometry were compared with the remodelling observed experimentally and showed good agreement. The tensile principal stress was found to be the best remodelling signal under the imposed conditions. Localized sensitivities in the remodelling patterns were found, however, and the definition of the dead zone was modified as a result. Remodelling with the new dead-zone definition showed that both the tensile principal stress and the tensile principal strain produced the remodelling patterns that agreed most closely with experiment. |
| Databáze: | OpenAIRE |
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