Sialylatin of glycoproteins of murine mammary tumor virus, murine leukemia virus, and Mason-Pfizer monkey virus
| Autor: | P. C. Kimball, Jeffrey Schlom, G Schochetman, R R Wagner, R H Schloemer |
|---|---|
| Rok vydání: | 1976 |
| Předmět: |
viruses
Immunology Neuraminidase Viral transformation Rauscher Virus Microbiology Virus Viral Proteins Mammary tumor virus Virology Tumor Virus Murine leukemia virus Animals Hemagglutination Viral Glycoproteins Cell-Free System biology Mouse mammary tumor virus Haplorhini biology.organism_classification Molecular biology Sialyltransferases Mammary Tumor Virus Mouse Insect Science Sialic Acids biology.protein Oncogenic Viruses Oncovirus Research Article |
| Zdroj: | Journal of Virology. 18:804-808 |
| ISSN: | 1098-5514 0022-538X |
| DOI: | 10.1128/jvi.18.2.804-808.1976 |
| Popis: | Neuraminidase treatment of mouse mammary tumor virus, Rauscher murine leukemia virus, and Mason-Pfizer monkey virus resulted in loss of their capacity to inhibit hemagglutination of influenza virus. Hemagglutination-inhibition activity of these RNA tumor viruses could be restored by in vitro resialylation catalyzed by sialyl transferase. The major glycoprotein in the intact envelope of desialylated and, to some extent, native virions could be specificallly labeled in vitro with CMP-(14C) sialic acid. These studies further characterize the individual glycoproteins of mouse mammary tumor virus, Rauscher murine leukemia virus, and Mason-Pfizer monkey virus. |
| Databáze: | OpenAIRE |
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