Nutritional Status of Patients with Chronic Obstructive Pulmonary Disease in Relation to their Physical Performance

Autor: Danijel Cvetko, Cristina Esquinas, Marko Zarak, Neven Tudorić, Zinka Matkovic, Dario Rahelić, Marc Miravitlles
Rok vydání: 2017
Předmět:
Male
Pulmonary and Respiratory Medicine
medicine.medical_specialty
Croatia
Cross-sectional study
Vital Capacity
Nutritional Status
Walk Test
Gastroenterology
Body Mass Index
Pulmonary Disease
Chronic Obstructive
03 medical and health sciences
Absorptiometry
Photon
0302 clinical medicine
Thinness
Forced Expiratory Volume
Surveys and Questionnaires
Internal medicine
Activities of Daily Living
medicine
Vitamin D and neurology
Humans
Prealbumin
Mass index
030212 general & internal medicine
Vitamin D
Exercise
Aged
Bone mineral
COPD
Exercise Tolerance
business.industry
Middle Aged
Anthropometry
medicine.disease
Walking Speed
Cross-Sectional Studies
Nutrition Assessment
Adipose Tissue
030228 respiratory system
Chronic obstructive pulmonary disease
body composition
exercise capacity
nutritional status
physical activity
Multivariate Analysis
Body Composition
Physical therapy
Lean body mass
Female
business
Body mass index
Zdroj: COPD: Journal of Chronic Obstructive Pulmonary Disease. 14:626-634
ISSN: 1541-2563
1541-2555
DOI: 10.1080/15412555.2017.1386643
Popis: Nutritional abnormalities and physical inactivity are highly prevalent in patients with chronic obstructive pulmonary disease (COPD). The aim of this study was to determine the association between nutritional status/body composition and physical performance in patients with COPD. A cross-sectional observational study was conducted in outpatients with clinically stable, moderate to very severe COPD. In the assessment of nutritional status, we used dual energy X-ray absorptiometry, anthropometry, serum biomarkers, and the Mini-Nutritional Assessment (MNA) questionnaire. Physical performance was measured by the 6-minute walk distance (6MWD), 4-metre gait speed (4MGS), and physical activity. Univariate and multivariate analyses were performed. In 111 patients (mean age 68 years, 69% men), the mean 6MWD was 376 ± 119 m, 4MGS 0.9 ± 0.2 m/s, and the average daily step count 8, 059 ± 4, 757. Patients with low exercise capacity (6MWD ≤ 350 m) had a significantly lower lean mass index (LMI) (p < 0.01), fat- free mass index (FFMI) (p < 0.01), bone mineral content (p < 0.01), bone mineral density (p < 0.01), T-score (p < 0.05), MNA score (p < 0.01), and serum albumin and prealbumin levels (p < 0.05). Patients with low physical activity (daily step count ≤ median) had lower LMI, FFMI, MNA score, serum prealbumin (for all comparisons p < 0.05) and vitamin D levels (p < 0.01). However, none of the nutritional variables showed an independent association with low physical performance in the multivariate models. In conclusion, patients with low physical performance have deficient nutritional status, but we could not demonstrate an independent relationship between nutritional parameters and physical performance.
Databáze: OpenAIRE
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