The Ability of Exercise to Mitigate Caloric Restriction-Induced Bone Loss in Older Adults: A Structured Review of RCTs and Narrative Review of Exercise-Induced Changes in Bone Biomarkers
| Autor: | Ryan M. Miller, Kristen M. Beavers, Sarah J. Wherry, Sarah H. Jeong |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
review lcsh:TX341-641 030209 endocrinology & metabolism law.invention 03 medical and health sciences 0302 clinical medicine bone loss Randomized controlled trial Weight loss law Bone Density Risk Factors Weight Loss Medicine Humans Obesity Caloric Restriction Randomized Controlled Trials as Topic Bone mineral mechanisms Nutrition and Dietetics exercise business.industry Caloric theory 030229 sport sciences medicine.disease Combined Modality Therapy Exercise Therapy Increased risk Treatment Outcome Physical therapy Osteoporosis Narrative review medicine.symptom business lcsh:Nutrition. Foods and food supply Biomarkers Osteoporotic Fractures Food Science |
| Zdroj: | Nutrients Nutrients, Vol 13, Iss 1250, p 1250 (2021) |
| ISSN: | 2072-6643 |
| Popis: | Despite the adverse metabolic and functional consequences of obesity, caloric restriction- (CR) induced weight loss is often contra-indicated in older adults with obesity due to the accompanying loss of areal bone mineral density (aBMD) and subsequent increased risk of fracture. Several studies show a positive effect of exercise on aBMD among weight-stable older adults; however, data on the ability of exercise to mitigate bone loss secondary to CR are surprisingly equivocal. The purpose of this review is to provide a focused update of the randomized controlled trial literature assessing the efficacy of exercise as a countermeasure to CR-induced bone loss among older adults. Secondarily, we present data demonstrating the occurrence of exercise-induced changes in bone biomarkers, offering insight into why exercise is not more effective than observed in mitigating CR-induced bone loss. |
| Databáze: | OpenAIRE |
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