Quantified TB Exposure Can Predict Prevalent TB Disease in Child Contacts
| Autor: | Farhana Amanullah, Hamidah Hussain, Sara Siddiqui, Jacob Creswell, Amyn A. Malik |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
Microbiology (medical)
Male medicine.medical_specialty Tuberculosis MEDLINE Disease Odds 03 medical and health sciences 0302 clinical medicine Unit increase 030225 pediatrics Internal medicine Surveys and Questionnaires Medicine Humans Mass Screening Pakistan 030212 general & internal medicine Child Family Characteristics business.industry Odds ratio medicine.disease Tb exposure Confidence interval Infectious Diseases Case-Control Studies Child Preschool Pediatrics Perinatology and Child Health Female Contact Tracing business |
| Zdroj: | The Pediatric infectious disease journal. 40(5) |
| ISSN: | 1532-0987 |
| Popis: | In a matched case-control study in Pakistan, we found that quantified tuberculosis (TB) exposure using a 10-point score is associated with prevalent TB disease in pediatric household contacts. A 1 unit increase in TB exposure score increased the odds of TB disease by 44% (conditional odds ratio: 1.44, 95% confidence interval: 1.33-1.56). Collecting well-documented exposure history can help TB diagnosis in resource-limited settings. |
| Databáze: | OpenAIRE |
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