Predictability in the evolution of Orthopteran cardenolide insensitivity

Autor: Hojun Song, Lu Yang, Nitin Ravikanthachari, Ricardo Mariño-Pérez, Krushnamegh Kunte, Adam Rosenstein, Riddhi Deshmukh, Mariana Wu, Peter Andolfatto
Rok vydání: 2019
Předmět:
0106 biological sciences
Insecticides
Insecta
Orthoptera
media_common.quotation_subject
Aposematism
Insect
Biology
Pyrgomorphidae
010603 evolutionary biology
01 natural sciences
General Biochemistry
Genetics and Molecular Biology
Insecticide Resistance
03 medical and health sciences
chemistry.chemical_compound
Pleiotropy
Convergent evolution
Gene duplication
Cardenolide
Animals
Amino Acid Sequence
Herbivory
Phylogeny
030304 developmental biology
media_common
Herbivore
0303 health sciences
biology.organism_classification
Biological Evolution
Cardenolides
chemistry
Evolutionary biology
Insect Proteins
Sodium-Potassium-Exchanging ATPase
Adaptation
Parallel evolution
General Agricultural and Biological Sciences
Sequence Alignment
Part II: Comparative Genomics and Convergent Evolution across Distantly Related Species
Zdroj: Philos Trans R Soc Lond B Biol Sci
ISSN: 1471-2970
0962-8436
DOI: 10.1098/rstb.2018.0246
Popis: The repeated evolutionary specialization of distantly related insects to cardenolide-containing host plants provides a stunning example of parallel adaptation. Hundreds of herbivorous insect species have independently evolved insensitivity to cardenolides, which are potent inhibitors of the alpha-subunit of Na + ,K + -ATPase (ATPα). Previous studies investigating ATPα-mediated cardenolide insensitivity in five insect orders have revealed remarkably high levels of parallelism in the evolution of this trait, including the frequent occurrence of parallel amino acid substitutions at two sites and recurrent episodes of duplication followed by neo-functionalization. Here we add data for a sixth insect order, Orthoptera, which includes an ancient group of highly aposematic cardenolide-sequestering grasshoppers in the family Pyrgomorphidae. We find that Orthopterans exhibit largely predictable patterns of evolution of insensitivity established by sampling other insect orders. Taken together the data lend further support to the proposal that negative pleiotropic constraints are a key determinant in the evolution of cardenolide insensitivity in insects. Furthermore, analysis of our expanded taxonomic survey implicates positive selection acting on site 111 of cardenolide-sequestering species with a single-copy of ATPα, and sites 115, 118 and 122 in lineages with neo-functionalized duplicate copies, all of which are sites of frequent parallel amino acid substitution. This article is part of the theme issue ‘Convergent evolution in the genomics era: new insights and directions’.
Databáze: OpenAIRE
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