Biological synthesis of gold and silver nanoparticles using leaf extracts of Crassocephalum rubens and their comparative in vitro antioxidant activities
| Autor: | Olusola B. Adewale, Bukola Tola Aluko, Jonathan Johnson, Kayode A. Egbeyemi, T. O. Obafemi, Olukemi Adetutu Osukoya, Amos Onasanya, Sotonye S. Potts-Johnson, Joan O. Onwuelu, Adewale Oluwaseun Fadaka, Scholastica O. Anadozie |
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| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
0301 basic medicine
Antioxidant medicine.medical_treatment Nanoparticle Extraction Silver nanoparticle 03 medical and health sciences 0302 clinical medicine medicine Nanotechnology Gold nanoparticles Surface plasmon resonance lcsh:Social sciences (General) lcsh:Science (General) Multidisciplinary biology Chemistry Extraction (chemistry) Crassocephalum rubens biology.organism_classification Materials science 030104 developmental biology Phytochemical Colloidal gold lcsh:H1-99 Silver nanoparticles 030217 neurology & neurosurgery Nuclear chemistry lcsh:Q1-390 Research Article |
| Zdroj: | Heliyon Heliyon, Vol 6, Iss 11, Pp e05501-(2020) |
| ISSN: | 2405-8440 |
| Popis: | The use of plant and plant products in the synthesis of silver nanoparticles (AgNPs) and gold nanoparticles (AuNPs) is made possible because of the natural inherent phytochemicals responsible for the reduction of respective metallic salts to nanoparticle forms, and ensuring therapeutic applicability. In this study, synthesis of AgNPs and AuNPs was performed using two different aqueous extraction methods for Crassocephalum rubens: maceration using laboratory method of extraction (cold aqueous extract of Crassocephalum rubens (AECR)), and decoction using traditional healer's method of extraction (hot aqueous crude extract of Crassocephalum rubens (CECR)). The synthesized nanoparticles were characterized using various methods, and in vitro antioxidant potential were thereafter investigated. The characterization results indicated the formation of mostly spherical-shaped AgNPs and AuNPs with surface plasmon resonance (SPR) band of 470 nm and 540 nm, respectively. The nanoparticles possess high antioxidant potentials but AECR synthesized AuNPs exhibited the least phytochemical contents and antioxidant potential when compared to other nanoparticles. It can therefore be concluded that extraction method and nanoparticle type are important factors that could influence the antioxidant properties of the nanoparticles. Further studies using these nanoparticles as anticancer or anti-inflammatory agent in both in vitro and in vivo are underway. Materials science; Nanotechnology; Antioxidant; Crassocephalum rubens; Extraction; Gold nanoparticles; Silver nanoparticles. |
| Databáze: | OpenAIRE |
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