Multi-center study of inter-rater reproducibility, image quality, and diagnostic accuracy of CZT versus conventional SPECT myocardial perfusion imaging

Autor: Nabeel Mansour, Stephan G. Nekolla, Eliana Reyes, George Angelidis, Panagiotis Georgoulias, Constantinos Anagnostopoulos, Paco Bravo, Isabella Bruno, Albert Flotats, Francisco Fuentes-Ocampo, Roberto Sciagrà, Felix Keng, Lukas Kessler, Maria Papathanasiou, Prem Soman, Christoph Rischpler
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: JOURNAL OF NUCLEAR CARDIOLOGY
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
instname
ISSN: 1071-3581
Popis: Background Cadmium-zinc-telluride (CZT)-based detectors exhibit higher diagnostic sensitivity in myocardial perfusion imaging (MPI) than conventional Anger-MPI for detection of coronary artery disease (CAD); however, reduced specificity and diagnostic accuracy of CZT-MPI were observed. This study aims to compare these different camera systems and to examine the degree of inter-rater reproducibility among readers with varying experience in MPI. Methods 83 patients who underwent double stress/rest examinations using both a CZT and conventional SPECT cameras within one visit were included. Anonymized and randomized MPI-images were distributed to 15 international readers using a standardized questionnaire. Subsequent coronary angiography findings of ten patients served as a reference for analysis of sensitivity and specificity. Results Image quality was significantly better in CZT-MPI with significantly lower breast attenuation (P P Conclusions Higher diagnostic sensitivity of CZT-MPI offers advantages in detection of CAD yet potentially of at the cost of reduced specificity, therefore it requires special training and a differentiated evaluation approach, especially for non-experienced readers with such camera systems.
Databáze: OpenAIRE
Externí odkaz: