Epidemiologically related and unrelated strains of Pseudomonas aeruginosa serotype O12 cannot be distinguished by phenotypic and genotypic typing
| Autor: | B. Picard, Joseph Watine, Charet Jc, C. Solignac-Bourrel, T.L. Pitt, A.J. Mifsud |
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| Rok vydání: | 1997 |
| Předmět: |
Microbiology (medical)
Serotype Male Genotype medicine.drug_class Antibiotics Microbial Sensitivity Tests medicine.disease_cause Microbiology Disease Outbreaks Pulsed-field gel electrophoresis medicine Humans Pseudomonas Infections Typing Bacteriophage Typing Aged Aged 80 and over Cross Infection biology Pseudomonas aeruginosa Outbreak Genetic Variation O Antigens General Medicine Middle Aged biology.organism_classification Virology Drug Resistance Multiple Bacterial Typing Techniques Electrophoresis Gel Pulsed-Field Infectious Diseases Phenotype Female France Polymorphism Restriction Fragment Length Pseudomonadaceae |
| Zdroj: | The Journal of hospital infection. 36(2) |
| ISSN: | 0195-6701 |
| Popis: | A clonal origin for European isolates of antibiotic multi-resistant Pseudomonas aeruginosa serotype O12 has been suggested. This study was designed to assess the value and limitations of several typing methods for the investigation of outbreaks due to this serotype. In Hopital de Rodez, France, this organism is endemic, and a prospective clinical epidemiological study was undertaken over a 15 month period, encompassing all patients at the hospital from whom P. aeruginosa O12 was isolated. All isolates were examined by auxanogram, antibiogram, phage-typing, electrophoresis of esterases and pulsed-field gel electrophoresis of DNA. The results suggest that (1) the methods used did not clearly differentiate between clinically-related and epidemiologically-unrelated European isolates, (2) in Hopital de Rodez, while some isolates were likely to have been transmitted from patientto-patient, most infections or colonizations with this organism were sporadic and their origin is unknown. The limits of typing methods for the investigation of outbreaks of nosocomial infection with multi-resistant P. aeruginosa O12 are emphasized. |
| Databáze: | OpenAIRE |
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