[1,2,4]Triazolo[3,4-b]benzothiazole scaffold as versatile nicotinamide mimic allowing nanomolar inhibition of different PARP enzymes

Autor:	Sudarshan Murthy, Maria Giulia Nizi, Mirko M. Maksimainen, Serena Massari, Juho Alaviuhkola, Barbara E. Lippok, Chiara Vagaggini, Sven T. Sowa, Albert Galera-Prat, Yashwanth Ashok, Harikanth Venkannagari, Renata Prunskaite-Hyyryläinen, Elena Dreassi, Bernhard Lüscher, Patricia Korn, Oriana Tabarrini, Lari Lehtiö
Jazyk:	angličtina
Rok vydání:	2023
Předmět:	Scaffolds Inhibitors Drug Discovery Molecular Medicine Reaction products ddc:610 Peptides and proteins Assays
Zdroj:	Journal of medicinal chemistry 66(2), 1301-1320 (2023). doi:10.1021/acs.jmedchem.2c01460
Popis:	Journal of medicinal chemistry 66(2), 1301-1320 (2023). doi:10.1021/acs.jmedchem.2c01460 Published by American Chemical Society, Washington, DC
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d02c78b88c3e04c15acc5405940609a1 http://urn.fi/urn:nbn:fi-fe2023032232837 Zobrazit plný text záznamu