Dataset of allele, genotype and haplotype frequencies of four polymorphisms filaggrin gene in Russian patients with atopic dermatitis
| Autor: | Natalya Rudykh, Irina Ponomarenko, Mikhail Churnosov, Tatyana Belyaeva, Anna Elykova, Alexey Polonikov, Evgeny Reshetnikov, Inna Aristova |
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| Rok vydání: | 2020 |
| Předmět: |
Male
Single-nucleotide polymorphism Biology lcsh:Computer applications to medicine. Medical informatics 03 medical and health sciences 0302 clinical medicine Biochemistry Genetics and Molecular Biology Genotype medicine Allele lcsh:Science (General) Atopic dermatitis 030304 developmental biology Genetic association Genetics 0303 health sciences Multidisciplinary Haplotype medicine.disease Single nucleotide polymorphism body regions Genetic marker lcsh:R858-859.7 Female FLG 030217 neurology & neurosurgery lcsh:Q1-390 Filaggrin |
| Zdroj: | Data in Brief, Vol 29, Iss, Pp-(2020) Data in Brief |
| ISSN: | 2352-3409 |
| DOI: | 10.1016/j.dib.2020.105307 |
| Popis: | Data on the allele, genotype and haplotype frequencies of four single nucleotide polymorphisms (SNPs) (rs3126085, rs12144049, rs471144 and rs4363385) filaggrin (FLG) gene in Russian patients with atopic dermatitis are presented. Genome-wide association studies identified these SNPs could be significant genetic markers associated with atopic dermatitis. The frequencies of alleles, genotypes and haplotypes of four SNPs were calculated in 3 groups: entire sample, females and males. No significant differences in the allele, genotype and haplotype frequencies between males and females with AD patients were observed. Keywords: Single nucleotide polymorphism, Atopic dermatitis, Female, Male, FLG |
| Databáze: | OpenAIRE |
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