The CaPTHUS score as predictor of multiglandular primary hyperparathyroidism in a European population
| Autor: | J. A. Jiménez-Ríos, N. Muñoz-Pérez, P. Notario-Fernández, J. I. Arcelus-Martínez, A. Molina-Raya, M. Dominguez-Bastante, Jesús Villar-del-Moral, M. Mogollón-González, M. Serradilla-Martín |
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| Rok vydání: | 2016 |
| Předmět: |
Male
Parathyroidectomy medicine.medical_specialty medicine.medical_treatment Population 030230 surgery 03 medical and health sciences 0302 clinical medicine Predictive Value of Tests medicine Humans Radionuclide Imaging education Aged Retrospective Studies Ultrasonography education.field_of_study Receiver operating characteristic business.industry Retrospective cohort study Middle Aged Vascular surgery Hyperparathyroidism Primary medicine.disease Surgery ROC Curve Parathyroid Hormone Spain 030220 oncology & carcinogenesis Predictive value of tests Calcium Female Radiology business Primary hyperparathyroidism Abdominal surgery |
| Zdroj: | Langenbeck's Archives of Surgery. 401:937-942 |
| ISSN: | 1435-2451 1435-2443 |
| Popis: | Focused parathyroidectomy has been proven to be a safe technique for the treatment of single-gland primary hyperparathyroidism (PHPT). The CaPTHUS scoring model has been reported to be an accurate preoperative diagnostic tool for distinguishing single-gland (SGD) from multiglandular disease (MGD), including preoperative serum calcium and PTH values plus ultrasound and Sestamibi scanning. The purpose of the present study was to validate the CaPTHUS model for the population in southern Europe, since the North American and the European populations show different clinicopathological profiles in PHPT. This is a retrospective review of a prospectively maintained database of patients diagnosed with PHPT who underwent surgical treatment in a single referral center. Differences between SGD and MGD groups were analyzed using chi-square and Fisher’s exact tests for categorical variables and Student’s t test for continuous variables. Overall diagnostic accuracy of the scoring model was assessed by the area under the receiver operating characteristic (ROC) curve (AUC). A p |
| Databáze: | OpenAIRE |
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