Experimental endogenous endophthalmitis caused by Haemophilus influenzae type b
Autor: | B L Johnson, R Klaw, R L Myerowitz |
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Rok vydání: | 1976 |
Předmět: |
Exudate
Haemophilus Infections Eye Diseases Haemophilus influenzae type Immunology Biology medicine.disease_cause Microbiology Haemophilus influenzae Lesion Endophthalmitis Lens Crystalline medicine Animals Panophthalmitis Inflammation medicine.disease Uveitis Anterior Rats Infectious Diseases Parasitology Phthisis bulbi medicine.symptom Uveitis Research Article |
Zdroj: | Infection and Immunity. 14:1043-1051 |
ISSN: | 1098-5522 0019-9567 |
DOI: | 10.1128/iai.14.4.1043-1051.1976 |
Popis: | Experimental endogenous endophthalmitis was produced in infant rats by either intranasal or intraperitoneal inoculation with Haemophilus influenzae type b and 5 days of age. The ocular disease occurred in about 50% of bacteremic animals who survived to age 12 days and probably represents metastatic bacterial infection secondary to hematogenous seeding. The lesion was a highly destructive suppurative endophthalmitis that ultimately progressed to panophthalmitis and was followed by organization of the exudate and phthisis bulbi. |
Databáze: | OpenAIRE |
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