Experimental endogenous endophthalmitis caused by Haemophilus influenzae type b

Autor: B L Johnson, R Klaw, R L Myerowitz
Rok vydání: 1976
Předmět:
Zdroj: Infection and Immunity. 14:1043-1051
ISSN: 1098-5522
0019-9567
DOI: 10.1128/iai.14.4.1043-1051.1976
Popis: Experimental endogenous endophthalmitis was produced in infant rats by either intranasal or intraperitoneal inoculation with Haemophilus influenzae type b and 5 days of age. The ocular disease occurred in about 50% of bacteremic animals who survived to age 12 days and probably represents metastatic bacterial infection secondary to hematogenous seeding. The lesion was a highly destructive suppurative endophthalmitis that ultimately progressed to panophthalmitis and was followed by organization of the exudate and phthisis bulbi.
Databáze: OpenAIRE