Risk Indicators for Congenital and Delayed-Onset Hearing Loss
Autor: | Casey T. Kraft, Angelique Boerst, Suparna Malhotra, Marc C. Thorne |
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Rok vydání: | 2014 |
Předmět: |
Male
Pediatrics medicine.medical_specialty Neonatal intensive care unit Databases Factual Hearing loss Logistic regression Risk Assessment law.invention Cohort Studies Neonatal Screening Audiometry Sodium Potassium Chloride Symporter Inhibitors Risk Factors law Intensive Care Units Neonatal otorhinolaryngologic diseases Humans Medicine Hearing Loss medicine.diagnostic_test business.industry Infant Newborn Length of Stay Intensive care unit Sensory Systems Aminoglycosides Logistic Models Otorhinolaryngology Cohort Female Neurology (clinical) medicine.symptom business Risk assessment Cohort study |
Zdroj: | Otology & Neurotology. 35:1839-1843 |
ISSN: | 1531-7129 |
DOI: | 10.1097/mao.0000000000000615 |
Popis: | Objective: To evaluate risk indicators for congenital and delayed onset hearing loss in a cohort of newborns who underwent newborn hearing screening, and to evaluate the impact of use of the Joint Committee on Infant Hearing (JCIH) recommendations on requirements for ongoing monitoring of infants identified as at risk for hearing loss. Patients and Methods: Cohort of 26,341 newborns entered in a prospectively collected database as part of the University of Michigan Universal Newborn Hearing Screening program, with 90 patients identified. Logistic regression analysis was used to evaluate putative risk indicators for congenital and delayed onset hearing loss. An estimate of the cost burden of ongoing monitoring imposed by the use of differing risk indicators was performed. Results: After controlling for the impact of other risk indicators, intensive care unit length of stay greater than 5 days and exposure to loop diuretics are not associated with an increased risk of congenital or delayed onset hearing loss. Inclusion of these risk indicators as a requirement for ongoing audiologic monitoring results in a high monitoring cost per additional case identified. Discussion: This study confirms that the majority of the risk indicators currently recommended by the JCIH are effective at identifying infants at increased risk of congenital and delayed onset hearing loss. However, use of neonatal intensive care unit length of stay greater than 5 days and exposure to ototoxic medications are associated with small gains in the number of infants correctly identified as at risk of hearing loss. Further evaluation of the utility of these risk indicators, preferably with a diversity of patient population and healthcare settings, is warranted. Key Words: Hearing lossVNeonatal screeningV Risk factors. Otol Neurotol 35:1839Y1843, 2014. |
Databáze: | OpenAIRE |
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