Cell-specific expression of LBP-32 mRNA in retina and other locations of newborn mouse eye as revealed by in situ hybridization
| Autor: | Gordon W. Laurie, C. M. Stone |
|---|---|
| Rok vydání: | 1992 |
| Předmět: |
Cell
Gene Expression In situ hybridization Biology Eye Epithelium Retina Cornea Cellular and Molecular Neuroscience Mice Lens Crystalline medicine Animals RNA Antisense RNA Messenger In Situ Hybridization Messenger RNA Choroid Molecular biology eye diseases Sensory Systems nervous system diseases Antisense RNA Mice Inbred C57BL Ophthalmology medicine.anatomical_structure Animals Newborn Oculomotor Muscles Lens (anatomy) Eye development sense organs Endothelium Vascular Laminin |
| Zdroj: | Current eye research. 11(9) |
| ISSN: | 0271-3683 |
| Popis: | LBP-32 is a cell surface and cytoplasmic protein which is thought to both mediate cell attachment to laminin and play a role in translation initiation. In the present study, antisense RNA for LBP-32 was used to document its cellular mRNA expression pattern in newborn mouse eye. In situ hybridization revealed that LBP-32 was distributed uniformly through the retina as well as over anterior oblique muscle, in corneal and lens epithelial cells and in capillary endothelial cells of the choroid. This unique cell-specific expression raises interesting questions of the role of LBP-32 in eye development. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|