CHOLANGIOCARCINOMA OF INTRAHEPATIC BILE DUCTS WITH DISSEMINATED METASTASES IN AN AFRICAN LION (PANTHERA LEO)
| Autor: | Elvio, Lepri, Monica, Sforna, Chiara, Brachelente, Brachelente, Chiara, Giovanni, Vitellozzi, Vitellozzi, Giovanni |
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| Rok vydání: | 2013 |
| Předmět: |
Lions
tumor Pathology medicine.medical_specialty Lung Neoplasms Intrahepatic bile ducts bile ducts Biology liver Panthera leo Bile Duct Carcinoma Tubular Pattern African lion cholangiocarcinoma medicine Animals Peritoneal Neoplasms General Veterinary Gallbladder Liver Neoplasms General Medicine medicine.disease Primary tumor medicine.anatomical_structure Bile Duct Neoplasms Liver Lobe Immunohistochemistry Female Animal Science and Zoology Lymph |
| Zdroj: | Journal of Zoo and Wildlife Medicine. 44:509-512 |
| ISSN: | 1937-2825 1042-7260 |
| DOI: | 10.1638/2012-0221r1.1 |
| Popis: | A cholangiocarcinoma is reported in an 18-yr-old, female African lion (Panthera leo). The primary tumor consisted of multifocal to coalescing, hepatic, white–yellow masses distributed throughout the liver lobes. Metastases were present in regional lymph nodes, peritoneal surface, and lungs. Histologically, the tumor was characterized by a tubular pattern with alcian- and periodic acid–Schiff–positive secretory material in cystic spaces. The neoplastic cells were positive to broad-spectrum cytokeratins. Histochemical and immunohistochemical stains were consistent with bile duct carcinoma. Biliary tumors arising from the gallbladder have been reported in lions. However, to the authors' knowledge, this is the first case of intrahepatic bile duct carcinoma reported in an African lion. |
| Databáze: | OpenAIRE |
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