Coexistence of granulomatosis with polyangiitis (GPA) and Crohn's disease or multiorgan manifestation of the same disease?
| Autor: | Izabela Ławnicka, Andrzej Książek, Lucyna Jóźwiak |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2016 |
| Předmět: |
Crohn’s disease
Pathology medicine.medical_specialty Immunology lcsh:Medicine Case Report ANCA antibody Disease macromolecular substances granulomatosis with polyangitis Inflammatory bowel disease 03 medical and health sciences 0302 clinical medicine Rheumatology Necrotizing Vasculitis medicine Immunology and Allergy Colitis Anti-neutrophil cytoplasmic antibody 030203 arthritis & rheumatology Crohn's disease business.industry lcsh:R medicine.disease digestive system diseases medicine.anatomical_structure 030211 gastroenterology & hepatology business Granulomatosis with polyangiitis Respiratory tract |
| Zdroj: | Reumatologia Rheumatology, Vol 54, Iss 2, Pp 86-90 (2016) |
| ISSN: | 2084-9834 0034-6233 |
| Popis: | Granulomatosis with polyangiitis (GPA) is a systemic necrotizing vasculitis of unknown aetiology, often related to the antineutrophil cytoplasmic antibody (ANCA). GPA was previously named Wegener’s granulomatosis (WG). The disease frequently has multisystemic presentation, targeting mainly the respiratory tract and kidneys, but gastrointestinal involvement is uncommon. Crohn’s disease (CD) is an inflammatory bowel disease (IBD) with many extraintestinal manifestations. Clinically, symptoms of WG and CD can mimic each other. In this paper a case of GPA manifested initially by severe multiorgan damage including colitis, regarded to be coexistent CD, is presented. The case illustrates the difficulties in establishing the diagnosis when symptoms of the diseases mimic each other. |
| Databáze: | OpenAIRE |
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