Limited surgery for benign tumours of the pancreas: a systematic review
| Autor: | M. Siech, Benjamin Mayer, M. H. Schoenberg, H. G. Beger, Bertram Poch |
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| Rok vydání: | 2015 |
| Předmět: |
Oncology
Reoperation medicine.medical_specialty medicine.medical_treatment Fistula Enucleation Gastroenterology Pancreatic Fistula Pancreatectomy Internal medicine medicine Humans Hospital Mortality business.industry medicine.disease Cardiac surgery Pancreatic Neoplasms Neuroendocrine Tumors medicine.anatomical_structure Cardiothoracic surgery Pancreatic fistula Surgery Pancreas business Neoplasms Cystic Mucinous and Serous Organ Sparing Treatments Abdominal surgery |
| Zdroj: | World journal of surgery. 39(6) |
| ISSN: | 1432-2323 |
| Popis: | Limited surgical procedures for benign cystic neoplasms and endocrine tumours of the pancreas have the potential advantage of pancreatic tissue sparing compared to standard oncological resections. Searching PubMed/MedLine, Embase and Cochrane Library identified 86 full papers: 25 reporting on enucleation (EN), 38 on central pancreatectomy (CP) and 23 on duodenum-preserving total/partial pancreatic head resection (DPPHRt/p). The results are based on analysis of data of 838, 912 and 431 patients for EN, CP and DPPHRt/s, respectively. The indication for EN for cystic neoplasms and neuro-endocrine tumours to EN was 20.5 and 73 %; for CP 62.9 and 31 %; and for DPPHRt/p 69.6 and 10.2 %, respectively. The estimated mean tumour sizes were in EN-group 2.4 cm, in CP-group 2.9 cm and in DPPHRt/p-group 3.1 cm (DPPHRt/p vs EN, p = 0.035). Postoperative severe complications developed after EN, CP and DPPHRt/p in 9.6, 16.8 and 11.5 % of patients; pancreatic fistula in 36.7, 35.2 and 20.1 %; and reoperation was required in 4.7, 6.5 and 1.8 %, respectively. Hospital mortality after EN was 0.95 %; after CP 0.72 %; and after DPPHRt/p 0.49 %. Compared to EN and CP, DPPHRt/p exhibited significant lower frequency of reoperation (p = 0.029, p |
| Databáze: | OpenAIRE |
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