Prevalence, management and ethnobotanical investigation of hypertension in two Guinean urban districts
| Autor: | Aliou Mamadou Balde, M. S. T. Diallo, Sophie Laurent, Emmy Tuenter, Aïssata Camara, K. Oulare, Luc Pieters, Mamadou Aliou Baldé, Robert N. Muller, M. Traoré, T.S. Diallo, Soumana Oumar Traoré, E.S. Baldé |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
Adult
Male medicine.medical_specialty Adolescent Ethnobotany Young Adult 03 medical and health sciences 0302 clinical medicine Drug Discovery Prevalence Humans Medicine Medicinal plants Medicine African Traditional Biology Uapaca Aged 030304 developmental biology Aged 80 and over Pharmacology 0303 health sciences Stem bark Plants Medicinal biology Traditional medicine business.industry Pharmacology. Therapy Public health Middle Aged biology.organism_classification Phytochemical 030220 oncology & carcinogenesis Hypertension Plant species Female Guinea Human medicine business Hymenocardia acida Phytotherapy |
| Zdroj: | Journal of ethnopharmacology |
| ISSN: | 0378-8741 |
| DOI: | 10.1016/j.jep.2018.07.028 |
| Popis: | Ethnopharmacological relevance Hypertension is an important public health challenge in low- and middle-income countries, and in many African countries including Guinea medicinal plants are still widely used for its treatment. Materials and Methods The objective of this study was to determine the prevalence of hypertension in two Guinean urban districts (Pounthioun and Dowsare), to describe its management and to collect information on traditional herbal remedies. A total of 316 participants entered the study, 28.2% (89/316) men and 71.8% (227/316) women. Of these, 181 were from Dowsare (50 men and 131 women) and 135 from Pounthioun (39 men and 96 women). The mean age of subjects was 40.8 ± 14.0 years (range18 − 88years), while the majority of subjects (63.3% or 200/316) were 45–74 years old. Results The overall prevalence of hypertension was 44.9% (142/316): 46.4% (84/181) from Dowsare and 43.0% (58/135) from Pounthioun. Ethnobotanical investigations among hypertensive patients led to the collection of 15 plant species, among which Hymenocardia acida leaves and Uapaca togoensis stem bark were the most cited. Phytochemical investigation of these two plant species led to the isolation and identification of isovitexin and isoorientin from H. acida, and betulinic acid and lupeol from U. togoensis. Conclusion The presence of these constituents in Hymenocardia acida leaves and Uapaca togoensis stem bark may at least in part support their traditional use against hypertension in Guinea. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full Text from ScienceDirect