Comparative 'Omics' of the Fusarium fujikuroi Species Complex Highlights Differences in Genetic Potential and Metabolite Synthesis
| Autor: | Robert H. Proctor, Yifat Idan, E. A. Tsavkelova, Danuše Tarkowská, Kristýna Hromadová, Meirav Elazar, Amir Sharon, Marcel Maymon, Petra M. Houterman, Bettina Tudzynski, Martin Münsterkötter, Petr Galuszka, Eva-Maria Niehaus, Ulrich Güldener, Abdel Baset A. Shalaby, Aleš Pěnčík, Immo Burkhardt, Sahar A. Youssef, Nelson L. Brock, Ondřej Novák, Christian M. K. Sieber, Daren W. Brown, El Said M. El-Shabrawy, Stanley Freeman, Liat Oren-Young, Jeroen S. Dickschat |
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| Přispěvatelé: | Molecular Plant Pathology (SILS, FNWI) |
| Rok vydání: | 2017 |
| Předmět: |
0301 basic medicine
Fusarium Fusarium fujikuroi species complex in planta expression Genome Endophyte Zea mays Host Specificity Evolution Molecular Fungal Proteins 03 medical and health sciences chemistry.chemical_compound Botany evolution Genetics Secondary metabolism Orchidaceae Fusarium Fujikuroi Species Complex Genome Sequencing Secondary Metabolism In Planta Expression Metabolomics Evolution Gene Ecology Evolution Behavior and Systematics Fungal protein secondary metabolism Mangifera Polymorphism Genetic biology food and beverages biology.organism_classification metabolomics Beauvericin ddc genome sequencing 030104 developmental biology chemistry Metabolome Genome Fungal Fusaric acid Research Article |
| Zdroj: | Genome Biology and Evolution Genome Biology and Evolution, 8(11), 3574-3599. Oxford University Press Genome Biol. Evol. 8, 3574-3599 (2016) |
| ISSN: | 1759-6653 |
| Popis: | Species of the Fusarium fujikuroi species complex (FFC) cause a wide spectrum of often devastating diseases on diverse agricultural crops, including coffee, fig, mango, maize, rice, and sugarcane. Although species within the FFC are difficult to distinguish by morphology, and their genes often share 90% sequence similarity, they can differ in host plant specificity and life style. FFC species can also produce structurally diverse secondary metabolites (SMs), including the mycotoxins fumonisins, fusarins, fusaric acid, and beauvericin, and the phytohormones gibberellins, auxins, and cytokinins. The spectrum of SMs produced can differ among closely related species, suggesting that SMs might be determinants of host specificity. To date, genomes of only a limited number of FFC species have been sequenced. Here, we provide draft genome sequences of three more members of the FFC: a single isolate of F. mangiferae, the cause of mango malformation, and two isolates of F. proliferatum, one a pathogen of maize and the other an orchid endophyte. We compared these genomes to publicly available genome sequences of three other FFC species. The comparisons revealed species-specific and isolate-specific differences in the composition and expression (in vitro and in planta) of genes involved in SM production including those for phytohormome biosynthesis. Such differences have the potential to impact host specificity and, as in the case of F. proliferatum, the pathogenic versus endophytic life style. |
| Databáze: | OpenAIRE |
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