Neuromuscular block and the electroencephalogram during sevoflurane anaesthesia
| Autor: | Rolf H. Sandin, Lars Brudin, Eva Sundman, Andreas Ekman, Lars Eriksson, Roland Flink |
|---|---|
| Rok vydání: | 2007 |
| Předmět: |
Adult
Male Methyl Ethers Adolescent Stimulation Electroencephalography Sevoflurane Monitoring Intraoperative Physical Stimulation medicine Noxious stimulus Humans General anaesthesia Prospective Studies Rocuronium Aged medicine.diagnostic_test business.industry musculoskeletal neural and ocular physiology General Neuroscience Myography Middle Aged Electric Stimulation Electrophysiology nervous system Anesthesia Bispectral index Data Interpretation Statistical Anesthetics Inhalation Female Neuromuscular Blocking Agents business Anesthesia Inhalation psychological phenomena and processes medicine.drug |
| Zdroj: | Neuroreport. 18(17) |
| ISSN: | 0959-4965 |
| Popis: | The effect of neuromuscular block on the anaesthetic depth of hypnosis is an elusive question. We simultaneously investigated the influence of neuromuscular block on the bispectral index, a measure of hypnosis during general anaesthesia, and on the electroencephalogram. Patients were anaesthetized with sevoflurane. Noxious tetanic electrical stimulation was applied on two occasions: before and after profound neuromuscular block achieved with rocuronium. Neuromuscular block significantly attenuated the effect from noxious stimulation on electroencephalogram power and synchrony in the gamma band (P0.05), and the corresponding effect on bispectral index (P0.02). These findings are probably due to the reduced arousing afferent input from paralysed muscles, and not to changes in the frontal electromyogram. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|