Acute impact of immediate release methylphenidate administered three times a day on sleep in children with attention-deficit/hyperactivity disorder
| Autor: | Sarah Ironside, Tracey Williams, Marilyn MacPherson, Rachel L. Panton, Penny Corkum |
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| Rok vydání: | 2007 |
| Předmět: |
Male
medicine.medical_specialty Pediatrics medicine.medical_treatment Polysomnography Biological Availability Drug Administration Schedule law.invention Sleep Apnea Syndromes Randomized controlled trial Double-Blind Method law Sleep Disorders Circadian Rhythm Surveys and Questionnaires Developmental and Educational Psychology medicine Attention deficit hyperactivity disorder Humans Psychiatry Child Cross-Over Studies medicine.diagnostic_test Methylphenidate Brain Actigraphy medicine.disease Stimulant Diagnostic and Statistical Manual of Mental Disorders Electrophysiology Attention Deficit Disorder with Hyperactivity Pediatrics Perinatology and Child Health Sleep diary Central Nervous System Stimulants Female Sleep onset latency Psychology Psychomotor Performance medicine.drug |
| Zdroj: | Journal of pediatric psychology. 33(4) |
| ISSN: | 1465-735X |
| Popis: | Objective To determine the impact of immediate release Ritalin, given three times a day, on sleep quality and quantity in medication-naive, newly diagnosed children with attention-deficit/hyperactivity disorder (ADHD). Methods Children (aged 6-12) rigorously diagnosed with ADHD (n ¼ 21) underwent multiple measurement assessments (i.e., actigraphy, sleep diary, and questionnaires) during a 1-week baseline and then during a 3-week blinded randomized medication trial. Results Although the medication was effective in reducing ADHD symptoms, analyses of actigraphy and sleep diary data found statistically and clinically significant changes in the children's total sleep time and sleep onset latency in the medication compared to the no medication conditions. No effects on sleep were found based on the sleep questionnaire. Conclusions Physicians and parents are encouraged to closely monitor children's sleep when treating ADHD with stimulant medication. |
| Databáze: | OpenAIRE |
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