Characteristics of slow pathway conduction after successful AVNRT ablation

Autor:	Uwais Mohamed, Basilios Petrellis, Damian P. Redfearn, Lorne J. Gula, Allan C. Skanes, Raymond Yee, Emoke Posan M.D., Andrew D. Krahn, Paul A. Gould, George J. Klein
Rok vydání:	2006
Předmět:	Tachycardia Adult Male medicine.medical_specialty Refractory Period Electrophysiological Slow pathway medicine.medical_treatment Catheter ablation Physiology (medical) Internal medicine medicine Humans Tachycardia Atrioventricular Nodal Reentry In patient business.industry Middle Aged Thermal conduction Ablation Surgery Radiofrequency catheter ablation cardiovascular system Cardiology Atrioventricular Node Catheter Ablation Female medicine.symptom Cardiology and Cardiovascular Medicine business
Zdroj:	Journal of cardiovascular electrophysiology. 17(8)
ISSN:	1045-3873
Popis:	AV node slow pathway conduction can persist following successful ablation for AV node reentrant tachycardia (AVNRT). We hypothesized that careful examination of AV nodal conduction curves before and after effective AVNRT ablation in patients with persistent slow pathway conduction could shed light on this apparent paradox.Thirty patients (age 40.9 +/- 14.3; 8 male) were included. AV node function curves were created based on pre- and postablation atrial extrastimulus testing. Analysis of slow pathway function curves demonstrated significant decrease in AH for any given coupling interval after ablation (mean difference -68.1 [-94.5, -41.7] P0.001), graphically indicated by downward displacement of the curve. In addition, mean slow pathway effective refractory period (ERP) increased from 247.9 +/- 36.1 msec to 288.6 +/- 56.0 msec (P0.001); mean maximum AH interval decreased from 361.3 +/- 114.2 msec to 306.9 +/- 65.2 msec (P = 0.013); mean difference in minimum and maximum AH interval during slow pathway conduction decreased (from 94.5 +/- 75.8 msec to 59.6 +/- 46.2 msec (P = 0.016). Finally, mean difference between the fast and slow pathway effective refractory periods, the span of coupling intervals over which slow pathway conduction occurred, decreased (from 113.9 +/- 61.4 msec to 63.2 +/- 41.5 msec, P = 0.001).Ablation, which successfully eliminates inducible and spontaneous AVNRT in the presence of persistent slow pathway conduction, is associated with significantly altered slow pathway conduction characteristics, indicating the presence of a damaged or different slow pathway after ablation, incapable of sustaining tachycardia.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfff4476435a92e6f6b9c342f2da5cbc https://pubmed.ncbi.nlm.nih.gov/16903963 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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