Response of Obese Patients to an 11 -Hydroxylase Inhibitor, Methopyrapone (SU-4885)
| Autor: | Benjamin Simkin, Rodrigo Arce |
|---|---|
| Rok vydání: | 1962 |
| Předmět: |
medicine.medical_specialty
Metyrapone Pyridines business.industry Urinary system medicine.medical_treatment Ketones General Biochemistry Genetics and Molecular Biology 17-Ketosteroids Mixed Function Oxygenases Steroid Excretion Endocrinology Internal medicine medicine Humans Obesity Methopyrapone business medicine.drug |
| Zdroj: | Experimental Biology and Medicine. 111:780-783 |
| ISSN: | 1535-3699 1535-3702 |
| DOI: | 10.3181/00379727-111-27921 |
| Popis: | SummaryObese subjects exhibit 2 different responses to an 11β-hydroxylase inhibitor, methopyrapone (SU-4885), depending upon the level of the base-line urinary 17-ketogenic steroid excretion. Subjects with a normal base-line 17-KGS excretion have a normal response to methopyrapone, whereas subjects with base-line elevated urinary 17-KGS give a markedly impaired response to this inhibitor. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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