Oral microbiota in xerostomia patients - A preliminary study
| Autor: | Cheng Chung Wei, Chih Chin Kao, Hui Wen Yang, Shir Ly Huang, Chen Tsung Weng, Yu-Feng Huang |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
Saliva Firmicutes Population Gastroenterology Xerostomia Actinobacteria stomatognathic system Internal medicine medicine education General Dentistry education.field_of_study biology business.industry Phylum Microbiota Bacteroidetes RK1-715 Fusobacteria biology.organism_classification stomatognathic diseases Sjogren's syndrome Dentistry Original Article Proteobacteria business |
| Zdroj: | Journal of Dental Sciences Journal of Dental Sciences, Vol 17, Iss 1, Pp 324-330 (2022) |
| ISSN: | 2213-8862 1991-7902 |
| Popis: | Background/purpose The estimated prevalence of xerostomia (lack of saliva) ranges from 10% to 50% of the general population. The oral cavity provides a multivariant environmental habitat to over 700 species of bacteria and fungi. We hypothesized that xerostomia will alter the composition of oral microbiota. Material and methods Nineteen xerostomia patients and 10 healthy normal volunteers were studied for the oral microbiota. Gingival plaques were collected and microbiota were detected using bacterial 16S ribosomal RNA and analyzed based on the levels of phylum and class. Results In all cases, phyla of Actinobacteria, Bacteroidetes, Firmicutes, Fusobacteria, and Proteobacteria make up to 100% of oral microbiota at phylum level. Analyzing individual phylum, presence of Bacteroidetes in xerostomia patients and normal subjects were 23.12 ± 2.56% and 23.23 ± 2.58%, respectively. Mean percentage presence of Firmicutes phylum in xerostomia patients and normal subjects were 18.94 ± 1.83% and 14.06 ± 0.98%, respectively. Statistically significant difference was not observed between xerostomia patients and normal subjects in this study. Conclusion These observations revealed obvious but not statistically significant changes in oral major microorganism phylum between xerostomia patients and normal subjects in this study. More samples are needed to verify the current results and to use oral microbiota as a tool in the diagnosis of xerostomia. |
| Databáze: | OpenAIRE |
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