The Functional Properties of Mg–Zn–X Biodegradable Magnesium Alloys
| Autor: | Alexei Vinogradov, Alexei Prokhorikhin, Tatiana V. Frolova, Alexander Brilevsky, Alexandra Tarkova, Pavel Myagkikh, Dmitry Merson, Evgeny Kretov |
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| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Materials science
Biocompatibility microstructure chemistry.chemical_element mechanical properties lcsh:Technology Article Corrosion General Materials Science Magnesium alloy lcsh:Microscopy lcsh:QC120-168.85 corrosion lcsh:QH201-278.5 lcsh:T Magnesium Biodegradable implants Metallurgy technology industry and agriculture magnesium alloy Microstructure bioresorbabale implants deformation processing Biodegradable magnesium chemistry lcsh:TA1-2040 cytotoxicity lcsh:Descriptive and experimental mechanics lcsh:Electrical engineering. Electronics. Nuclear engineering Severe plastic deformation lcsh:Engineering (General). Civil engineering (General) lcsh:TK1-9971 |
| Zdroj: | 544-? Materials Volume 13 Issue 3 Materials, Vol 13, Iss 3, p 544 (2020) |
| Popis: | The implantation of metallic devices in orthopaedic surgical procedures and coronary angioplasty is associated with the risk of various adverse events: (i) mechanical (premature failure), (ii) chemo-mechanical (corrosion and corrosion-fatigue degradation) and (iii) biomedical (chronic local inflammatory reactions, tissue necrosis, etc.). In this regard, the development of biodegradable implants/stents, which provide the necessary mechanical support for the healing period of the bone or the vessel wall and then are completely resorbed, has bright prospects. Magnesium alloys are the most suitable candidates for that purpose due to their superior mechanical performance, bioresorbability and biocompatibility. This article presents the results of the comparative research on several wrought biodegradable alloys, assessing their potential for biomedical applications. The Mg&ndash Zn&ndash X alloys with different chemical compositions and microstructures were produced using severe plastic deformation techniques. Functional properties pivotal for biomedical applications&mdash mechanical strength, in vitro corrosion resistance and cytotoxic activity&mdash were included in the focus of the study. Excellent mechanical performance and low cytotoxic effects are documented for all alloys with a notable exception for one of two Mg&ndash Zr alloys. The in vitro corrosion resistance is, however, below expectations due to critical impurities, and this property has yet to be drastically improved through the cleaner materials fabrication processing before they can be considered for biomedical applications. |
| Databáze: | OpenAIRE |
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