Secular changes in bone mineral density of adult Japanese women from 1995 to 2013
| Autor: | Yumi Watanabe, Yasuko Minagawa, Ichiro Suzuki, Hiroaki Watanabe, Aya Hinata, Keiko Kabasawa, Kazutoshi Nakamura, Kaori Kitamura, Kseniia Platonova |
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| Rok vydání: | 2021 |
| Předmět: |
Adult
musculoskeletal diseases Bone density Osteoporosis Population secular change BMI Absorptiometry Photon Japan Forearm medicine Humans education Bone mineral Hip fracture education.field_of_study business.industry Incidence Incidence (epidemiology) bone density General Medicine Middle Aged medicine.disease osteoporosis Secular variation medicine.anatomical_structure Original Article Female women business Demography |
| Zdroj: | Fukushima Journal of Medical Science |
| ISSN: | 2185-4610 0016-2590 |
| DOI: | 10.5387/fms.2021-10 |
| Popis: | Introduction: Secular changes in hip fracture incidence have been reported in the last few decades in Japan, but whether long-term bone mineral density (BMD) is also changing is unclear. This study aimed to determine whether BMD of Japanese women has changed over time. Methods: Subjects were 10,649 adult women who underwent BMD measurement in a health check-up population in Niigata, Japan, between 1995 and 2013. BMD of the distal, non-dominant forearm was measured by dual-energy X-ray absorptiometry. Demographic information and BMI were also obtained. Secular trends were determined by linear regression analysis. Results: BMD of subjects in their 40’s decreased significantly in the age-adjusted model (P for trend=0.0162), but not in the age- and BMI-adjusted model (P for trend=0.2171). BMD of subjects in their 50’s decreased marginally in the age-adjusted model (P for trend=0.0535), but not in the age- and BMI-adjusted model (P for trend=0.6601). BMDs of subjects in their 30’s and 60’s did not significantly change, while BMIs of subjects in their 40’s-60’s decreased significantly. Conclusions: A secular decrease in BMD, partly attributed to decreases in BMI, was observed in middle-aged Japanese women from 1995 to 2013. Measures to help maintain suitable BMI will be necessary to prevent a decrease in BMD among women. |
| Databáze: | OpenAIRE |
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