Modelling and characterization of a pneumatically actuated peristaltic micropump
| Autor: | V. A. Petrov, A.I. Khaustov, E. V. Trushkin, T. N. Gerasimenko, O.V. Kindeeva |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2016 |
| Předmět: |
Engineering
business.industry Applied Mathematics 010401 analytical chemistry Microfluidics Fluid Dynamics (physics.flu-dyn) Micropump Mechanical engineering FOS: Physical sciences 02 engineering and technology Physics - Fluid Dynamics 021001 nanoscience & nanotechnology 01 natural sciences Viscoelasticity 0104 chemical sciences Characterization (materials science) Volumetric flow rate Physics::Fluid Dynamics Flow (mathematics) Modeling and Simulation 0210 nano-technology business Displacement (fluid) Peristalsis |
| Popis: | There is an emerging class of microfluidic bioreactors which possess long-term, closed circuit perfusion under sterile conditions with in vivo-like flow parameters. Integrated into microfluidics, peristaltic-like pneumatically actuated displacement micropumps are able to meet these requirements. We present both a theoretical and experimental characterization of such pumps. In order to examine volume flow rate, we have developed a mathematical model describing membrane motion under external pressure. The viscoelasticity of the membrane and hydrodynamic resistance of the microfluidic channel have been taken into account. Unlike other models, the developed model includes only the physical parameters of the pump and allows the estimation of their impact on the resulting flow. The model has been validated experimentally. |
| Databáze: | OpenAIRE |
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