Concordance with the World Cancer Research Fund/American Institute for Cancer Research recommendations for cancer prevention and colorectal cancer risk in Morocco: A large, population‐based case–control study
| Autor: | Hind Mrabti, A. Benslimane, Meimouna Mint Sidi Deoula, Chakib Nejjari, Karima El Rhazi, Inge Huybrechts, Hanae Abir Boudouaya, Ellen Kampman, Naima Abda, Achraf El Asri, Rhimou Alaoui, Zineb Hatime, Sidi Adil Ibrahimi, Khaoula El Kinany, Marc J. Gunter |
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| Rok vydání: | 2019 |
| Předmět: |
Adult
Male Cancer Research medicine.medical_specialty Nutrition and Disease Colorectal cancer Concordance colorectal cancer FFQ Body Mass Index Food group Tumours of the digestive tract Radboud Institute for Health Sciences [Radboudumc 14] 03 medical and health sciences 0302 clinical medicine case–control study FFQ Morocco Voeding en Ziekte Internal medicine medicine Humans Exercise Societies Medical VLAG Aged WCRF/AICR recommendations Cancer prevention business.industry Incidence Confounding Case-control study case–control study Middle Aged Anthropometry Nutrition Surveys medicine.disease United States Confidence interval Morocco Oncology Case-Control Studies Sample Size 030220 oncology & carcinogenesis Patient Compliance Female Colorectal Neoplasms business |
| Zdroj: | International Journal of Cancer, 145, 7, pp. 1829-1837 International Journal of Cancer, 145(7), 1829-1837 International Journal of Cancer, 145, 1829-1837 International Journal of Cancer 145 (2019) 7 |
| ISSN: | 1097-0215 0020-7136 |
| DOI: | 10.1002/ijc.32263 |
| Popis: | Item does not contain fulltext The present study aimed to investigate associations between adherence to the recommendations on cancer prevention from the WCRF/AICR and colorectal cancer (CRC) risk in Morocco. Incident CRC cases (n = 1,516) and controls (n = 1,516) matched on age, sex and center, were recruited between September 2009 and February 2017 at five major hospitals located in Morocco. In-person interviews were conducted to assess habitual diet using a validated Food Frequency Questionnaire, physical activity and anthropometric measurements. Adherence to the WCRF/AIRC Recommendations was ranged from 0 (no adherence) to 6 (maximal adherence) and incorporating six WCRF/AICR components (food groups, physical activity and BMI). Multivariable odd ratios (ORA ) and 95% confidence intervals (CI) were calculated using conditional multivariate logistic regression models, with low adherence as referent, adjusting for potential confounding factors. Compared to those with the lowest adherence score, individuals in the highest WCRF/AICR score category had a statistically significant reduced risk for colon cancer (ORA = 0.63, 95% CI 0.53-0.76); rectal cancer (ORA = 0.52, 95% CI 0.43-0.63) and CRC overall (ORA = 0.58, 95% CI 0.51-0.66). For individual score components, when comparing the lowest with the highest adherence category, CRC risk was significantly lower in the highest adherence category for body fatness (ORA = 0.73; 95% CI 0.62-0.85), physical activity (ORA = 0.70; 95% CI 0.60-0.82), plant foods (ORA = 0.50; 95% CI 0.39-0.63) and red/processed meat (ORA = 0.81; 95% CI 0.71-0.92). Our analysis indicated that greater adherence to the WCRF/AICR recommendations for cancer prevention may lower CRC risk in Morocco. |
| Databáze: | OpenAIRE |
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