Neurological and Mental Health Symptoms Associated with Post-COVID-19 Disability in a Sample of Patients Discharged from a COVID-19 Ward: A Secondary Analysis
| Autor: | Martina Cacciatore, Alberto Raggi, Andrea Pilotto, Viviana Cristillo, Erika Guastafierro, Claudia Toppo, Francesca G. Magnani, Davide Sattin, Arianna Mariniello, Fabiola Silvaggi, Stefano Cotti Piccinelli, Nicola Zoppi, Giulio Bonzi, Stefano Gipponi, Ilenia Libri, Michela Bezzi, Paolo Martelletti, Matilde Leonardi, Alessandro Padovani |
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| Rok vydání: | 2022 |
| Předmět: |
Male
hyposmia Health Toxicology and Mutagenesis hypogeusia Public Health Environmental and Occupational Health COVID-19 Anxiety anxiety brain impairment cognitive dysfunction disability fatigue WHODAS-12 aged cohort studies Hospitals humans male mental health Cohort Studies Mental Health Humans Aged |
| Zdroj: | International Journal of Environmental Research and Public Health; Volume 19; Issue 7; Pages: 4242 |
| ISSN: | 1660-4601 |
| Popis: | Recent studies suggest that COVID-19 survivors may experience long-term health consequences: in particular, neurological and mental health symptoms might be associated with long-term negative outcomes. This study is a secondary analysis of a larger cohort study and aims to determine the extent to which neurological and mental health sequelae are associated with survivors’ disability. Participants include COVID-19 survivors, with no pre-morbid brain conditions, who were discharged from the COVID-19 Unit of the ASST Spedali Civili Hospital between February and April 2020. At an average of 3.5 months after discharge, they were submitted to a neurological examination and completed the WHO Disability Assessment Schedule (WHODAS-12), the Hospital Anxiety and Depression Score, the Pittsburgh Sleep Quality Index and the Montreal Cognitive Assessment. Multivariable regression analysis was carried out to analyze variables that explain WHODAS-12 variation. In total, 83 patients (63 males, average age 66.9, 95% CI: 64.2–69.7) were enrolled; average WHODAS-12 was 13.2 (95% CI: 9.7–16.6). Cognitive dysfunction, anxiety, fatigue, and hyposmia/hypogeusia explained 28.8% of WHODAS-12 variation. These findings underline the importance and need for longitudinal follow-up assessments after recovery from COVID-19 and suggest the need for early rehabilitation of residual symptoms to enhance patients’ functioning. |
| Databáze: | OpenAIRE |
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