Gallstone Disease is an Independent Predictor for Poststroke Cognitive Impairment in Young Patients with Acute Ischemic Stroke
| Autor: | Yi Ling, Weilai Chen, Jing Sun, Fangwang Fu, Xiongpeng Weng |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
Adult
Male medicine.medical_specialty Disease Gallstones Logistic regression Cohort Studies Risk Factors Internal medicine medicine Humans Cognitive Dysfunction cardiovascular diseases Prospective Studies Cognitive impairment Acute ischemic stroke Aged business.industry Public health Gallbladder Cognition Middle Aged Stroke surgical procedures operative medicine.anatomical_structure Logistic Models Neurology Conventional PCI Female Neurology (clinical) business |
| Zdroj: | European neurology. 82(1-3) |
| ISSN: | 1421-9913 |
| Popis: | Background: Poststroke cognitive impairment (PCI) is an important public health issue. Previous studies proved that gallstone disease (GD) was a predictor for cardiovascular and cerebrovascular disease. However, association between PCI and GD remains unclear. We aimed to investigate the predictive value of GD on cognitive impairment after acute ischemic stroke (AIS). Methods: We recruited 373 AIS patients, and the information on patient demographics and risk factors was collected. Cognitive function would be assessed 3-month after AIS. They would undergo gallbladder ultrasonographic examination and structured assessment during hospitalization. Patients were divided into young group (age Results: PCI was identified in 176 (47.18%) AIS patients. Independent predictors of PCI were GD (p = 0.014), the National Institutes of Health Stroke Scale score and age. While carotid plaque (p = 0.058) seemed like a potential risk factor for PCI. In young group, GD (p = 0.027) was associated to PCI, in elder group, carotid plaque (p = 0.006), and age (p = 0.033) were significantly correlated to PCI. Conclusion: GD was an age-dependent predictor for PCI, particularly in the young AIS patients. Therefore, AIS patients with GD, especially the young, should be systematically evaluated for cognitive function. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|