Effect of water diuresis and water restriction on expression of HSPs-27, -60 and -70 in rat kidney
| Autor: | Lloyd G. Cantley, Ruth Medina, Franklin H. Epstein, Kate Spokes |
|---|---|
| Rok vydání: | 1996 |
| Předmět: |
Male
medicine.medical_specialty Kidney Cortex Renal cortex Urinary system Blotting Western 030232 urology & nephrology Biology Kidney Rats Sprague-Dawley 03 medical and health sciences 0302 clinical medicine Heat shock protein Internal medicine medicine Renal medulla Animals HSP70 Heat-Shock Proteins RNA Messenger Heat-Shock Proteins 030304 developmental biology 0303 health sciences Kidney Medulla Osmotic concentration Water Deprivation Chaperonin 60 Blotting Northern 6. Clean water Diuresis Rats Major duodenal papilla medicine.anatomical_structure Endocrinology Nephrology Renal papilla |
| Zdroj: | Kidney International. 50(4):1191-1194 |
| ISSN: | 0085-2538 |
| DOI: | 10.1038/ki.1996.427 |
| Popis: | Effect of water diuresis and water restriction on expression of HSPs-27, -60 and -70 in rat kidney. Expression of HSP-27, HSP-60 and HSP-70 was estimated in the cortex, outer medulla and inner medulla (papilla) of rats undergoing water diuresis or water restriction for two days. The mRNAs for HSP-27 and HSP-60 in renal papilla were two- to threefold greater in rats during water restriction than in those excreting a dilute urine, but levels of mRNA for HSP-70 were not reduced by water diuresis and Western analysis for HSP-70 protein showed no difference between water-loaded and water-restricted animals. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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