Compliance with local guidelines for antibiotic prophylaxis in surgery
| Autor: | Jordi Delás, Montserrat Pons-Busom, Margarita Aguas-Compaired, Begoña Eguileor-Partearroyo |
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| Rok vydání: | 2004 |
| Předmět: |
Microbiology (medical)
Male medicine.medical_specialty Epidemiology medicine.drug_class Antibiotics Cefazolin Pharmacy Drug Utilization Review Acute care Medicine Humans Medical prescription Antibiotic prophylaxis Antibacterial agent Infection Control business.industry Antibiotic Prophylaxis Middle Aged Surgery Infectious Diseases Cross-Sectional Studies Spain Chemoprophylaxis Practice Guidelines as Topic Female Guideline Adherence business Pharmacy Service Hospital medicine.drug Compliance |
| Zdroj: | Infection control and hospital epidemiology. 25(4) |
| ISSN: | 0899-823X 0195-9417 |
| Popis: | Objectives:To describe the development and implementation of a local protocol for antibiotic prophylaxis in surgery and to assess compliance with these guidelines using a computer-based system.Design:One 5-week prospective period (phase 1) followed by three 1-week, cross-sectional assessments (phases 2, 3, and 4).Setting:Pharmacy of a 350-bed acute care teaching hospital in Barcelona, Spain.Methods:In phase 1, 395 forms for antibiotic prescribing delivered to the pharmacy were reviewed. Nonadherence was defined as the prescription of an antibiotic (or doses) different from what the protocol specified. In phases 2, 3, and 4, antibiotic prescribing forms for all elective procedures (630 patients) performed during 1-week periods were analyzed.Results:A total of 1,047 patients (mean age, 58.9 ± 17.3 years) were included. Cefazolin was administered in 41% of procedures. Overall compliance with antibiotic prescribing forms was 83.3%. There was a statistically significant increase in compliance with guidelines throughout the four phases of the study, from 80.3% in phase 1 to 87.8% in phase 4 (P< .042), as well as adherence to completing forms for surgical procedures, from 51% in phase 2 to 77.6% in phase 4 (P< .001). The main reason for non-adherence was that some procedures had not been included in the protocol in phase 2.Conclusion:Surgeons sensitized to the implementation of local antibiotic prophylaxis guidelines showed a high degree of compliance with them, using both the procedure established for antibiotic prescribing and the antimicrobials recommended for particular operations. |
| Databáze: | OpenAIRE |
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