Risk factors for extended-spectrum β-lactamase positivity in uropathogenic Escherichia coli isolated from community-acquired urinary tract infections
| Autor: | Funda Timurkaynak, Sule Colakoglu, Özlem Kurt Azap, Süheyla Serin Senger, K. Şerefhanoğlu, Haluk Erdoğan, Hande Arslan |
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| Rok vydání: | 2010 |
| Předmět: |
Male
Turkey medicine.medical_treatment Antibiotics Polymerase Chain Reaction Cohort Studies Community-acquired urinary tract infection Pregnancy Uropathogenic Escherichia coli risk factors Prospective Studies Prospective cohort study Escherichia coli Infections Escherichia coli Proteins Sulfamethoxazole ESBL positivity General Medicine Middle Aged Anti-Bacterial Agents Community-Acquired Infections Ciprofloxacin Infectious Diseases Urinary Tract Infections Female Gentamicin medicine.drug Adult DNA Bacterial Microbiology (medical) medicine.medical_specialty Adolescent medicine.drug_class Microbial Sensitivity Tests Biology beta-Lactamases Microbiology Young Adult Internal medicine medicine Animals Humans Risk factor Aged E. coli Sequence Analysis DNA biochemical phenomena metabolism and nutrition bacterial infections and mycoses Trimethoprim ESBL enzyme types Beta-lactamase |
| Zdroj: | Clinical Microbiology and Infection. 16:147-151 |
| ISSN: | 1198-743X |
| DOI: | 10.1111/j.1469-0691.2009.02941.x |
| Popis: | The aim of this prospective cohort study was to determine the risk factors for community-acquired urinary tract infections (UTIs) caused by extended-spectrum beta-lactamase (ESBL)-positive Escherichia coli and the distribution of the ESBL enzyme types. Structured forms were filled in for patients diagnosed with community-acquired UTI in four different geographical locations in Turkey. The forms and the isolates were sent to the central laboratory at Baskent University Hospital, Ankara. Antimicrobial susceptibility was determined according to the CLSI criteria. PCR and DNA sequencing were used to characterize the bla(TEM), bla(CTX-M) and bla(SHV) genes. Multivariate analysis was performed using logistic regression. A total of 510 patients with UTI caused by Gram-negative bacteria were included in this study. ESBLs were detected in 17 of 269 (6.3%) uropathogenic E. coli isolates from uncomplicated UTIs and 34 of 195 (17.4%) E. coli isolates from complicated UTIs (p |
| Databáze: | OpenAIRE |
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