Lesion index: a novel guide in the path of successful pulmonary vein isolation
| Autor: | Benedetta Majocchi, Massimo Moltrasio, Fabrizio Tundo, Alessio Gasperetti, Gaetano Fassini, Michela Casella, Salvatore Pala, Gabriele Negro, Valentina Catto, Francesca Pizzamiglio, Martina Zucchetti, Corrado Carbucicchio, Antonio Russo, Valentina Ribatti, Maria Antonietta Dessanai, Elena Romanelli, Rita Sicuso, Claudio Tondo, Giulia Vettor, Stefania Riva, Selene Cellucci |
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| Rok vydání: | 2018 |
| Předmět: |
Epicardial Mapping
Male medicine.medical_specialty medicine.medical_treatment Catheter ablation Right superior pulmonary vein 030204 cardiovascular system & hematology Pulmonary vein Lesion 03 medical and health sciences Electrocardiography 0302 clinical medicine Recurrence Physiology (medical) Internal medicine Atrial Fibrillation medicine Humans 030212 general & internal medicine Retrospective Studies Radiofrequency Ablation Receiver operating characteristic business.industry Atrial fibrillation Middle Aged medicine.disease Right inferior pulmonary vein Catheter Echocardiography Pulmonary Veins Cardiology Female medicine.symptom Cardiology and Cardiovascular Medicine business |
| Zdroj: | Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing. 55(1) |
| ISSN: | 1572-8595 |
| Popis: | Previous studies indicate force time integral (FTI) as a radiofrequency (RF) lesion quality marker, while not considering power supply. Tacticath™ Quartz catheter provides Lesion index (LSI), a lesion quality marker derived by contact force (CF), power supply, and RF time combined. Our aim is to assess LSI and FTI correlation and a LSI-related cutoff of atrial fibrillation (AF) recurrences 12 months after pulmonary vein isolation (PVI). We retrospectively enrolled 37 patients who underwent RF ablation using Tacticath™ Quartz catheter. AF recurrence rate was evaluated 3, 6, and 12 months after PVI procedure. AF recurrence was detected in 32% of patients. FTI mean value was significantly lower in left superior pulmonary vein (LSPV: 256 ± 86 gs vs 329 ± 117 gs, p = 0.05) and right inferior pulmonary vein (RIPV: 253 ± 128 gs vs 394 ± 123 gs p = 0.006) in patients with AF recurrences; no significant differences were found in right superior pulmonary vein (RSPV) and left inferior pulmonary vein (LIPV). LSI instead was significantly higher for all veins in patients without AF recurrences: LSPV (5.2 ± 0.7 vs 4.6 ± 0.8, p = 0.03), LIPV (5.0 ± 0.8 vs 4.5 ± 0.6, p = 0.04), RSPV (5.5 ± 0.6 vs 5.1 ± 0.6, p = 0.05), and RIPV (5.5 ± 0.7 vs 4.7 ± 0.8, p = 0.006). Receiver operator characteristic curve suggests 5.3 as LSI overall cutoff value predicting freedom from disease at 1-year follow-up. Our preliminary data suggest that a LSI mean value higher than 5.3 can be considered a good predictor of AF freedom at 1-year follow-up. |
| Databáze: | OpenAIRE |
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